[HTML][HTML] Camellia sinensis: insights on its molecular mechanisms of action towards nutraceutical, anticancer potential and other therapeutic applications

P Chaudhary, D Mitra, PKD Mohapatra… - Arabian Journal of …, 2023 - Elsevier
The Camellia sinensis plant provides a wide diversity of black, green, oolong, yellow, brick
dark, and white tea. Tea is one of the majorly used beverages across the globe, succeeds …

Parkinson's disease: exploring different animal model systems

E Khan, I Hasan, ME Haque - International journal of molecular sciences, 2023 - mdpi.com
Disease modeling in non-human subjects is an essential part of any clinical research. To
gain proper understanding of the etiology and pathophysiology of any disease, experimental …

Neuroprotective effects of pomegranate juice against Parkinson's disease and presence of ellagitannins-derived metabolite—urolithin A—in the brain

M Kujawska, M Jourdes, M Kurpik, M Szulc… - International journal of …, 2019 - mdpi.com
Pomegranate juice is a rich source of ellagitannins (ETs) believed to contribute to a wide
range of pomegranate's health benefits. While a lot of experimental studies have been …

The association between lifestyle factors and Parkinson's disease progression and mortality

KC Paul, YH Chuang, IF Shih, A Keener… - Movement …, 2019 - Wiley Online Library
Background Lifestyle factors may contribute to the development of Parkinson's disease, but
little is known about factors that influence progression. The objective of the current study was …

Caffeic acid improves locomotor activity and lessens inflammatory burden in a mouse model of rotenone-induced nigral neurodegeneration: Relevance to Parkinson's …

SA Zaitone, E Ahmed, NM Elsherbiny… - Pharmacological …, 2019 - Springer
Background Caffeic acid phenethyl ester is found in honey bee propolis. It has
immunomodulatory, anti-inflammatory and anti-cancer properties. Rotenone is a pesticide …

Neuroprotective effects of catechin and quercetin in experimental Parkinsonism through modulation of dopamine metabolism and expression of IL-1β, TNF-α, NF-κB …

SS Josiah, CD Famusiwa, OO Crown, AO Lawal… - Neurotoxicology, 2022 - Elsevier
The neurobehavioral, brain redox-stabilizing and neurochemical modulatory properties of
catechin and quercetin in rotenone-induced Parkinsonism, and the involvement of NF-κB …

Barbigerone potentially alleviates rotenone-activated Parkinson's disease in a rodent model by reducing oxidative stress and neuroinflammatory cytokines

KM Alharthy, HN Althurwi, FF Albaqami, A Altharawi… - ACS …, 2023 - ACS Publications
Background: Parkinson's disease (PD) is a common age-related and slowly progressive
neurodegenerative disease that affects approximately 1% of the elderly population. In recent …

Protective effect of (−) epigallocatechin-3-gallate on rotenone-induced parkinsonism-like symptoms in rats

HC Tseng, MH Wang, KC Chang, HS Soung… - Neurotoxicity …, 2020 - Springer
Rotenone (ROT)-induced neurotoxicity has been used for decades as an animal model of
Parkinson's disease (PD) in humans. This model exhibits pathophysiological features similar …

Methylxanthines and neurodegenerative diseases: An update

D Janitschke, AA Lauer, CM Bachmann, HS Grimm… - Nutrients, 2021 - mdpi.com
Methylxanthines (MTX) are purine derived xanthine derivatives. Whereas naturally occurring
methylxanthines like caffeine, theophylline or theobromine are widely consumed in food …

Sex differences in rotenone sensitivity reflect the male-to-female ratio in human Parkinson's disease incidence

BR De Miranda, M Fazzari, EM Rocha… - Toxicological …, 2019 - academic.oup.com
There is a critical need to include female subjects in disease research; however, in
Parkinson's disease, where the male-to-female incidence is about 1.5-to-1, the majority of …