A review of animal models of intervertebral disc degeneration: pathophysiology, regeneration, and translation to the clinic
Lower back pain is the leading cause of disability worldwide. Discogenic pain secondary to
intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is …
intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is …
What is intervertebral disc degeneration, and what causes it?
MA Adams, PJ Roughley - Spine, 2006 - journals.lww.com
Study Design. Review and reinterpretation of existing literature. Objective. To suggest how
intervertebral disc degeneration might be distinguished from the physiologic processes of …
intervertebral disc degeneration might be distinguished from the physiologic processes of …
Are animal models useful for studying human disc disorders/degeneration?
Intervertebral disc (IVD) degeneration is an often investigated pathophysiological condition
because of its implication in causing low back pain. As human material for such studies is …
because of its implication in causing low back pain. As human material for such studies is …
The role of the vertebral end plate in low back pain
End plates serve as the interface between rigid vertebral bodies and pliant intervertebral
disks. Because the lumbar spine carries significant forces and disks don't have a dedicated …
disks. Because the lumbar spine carries significant forces and disks don't have a dedicated …
Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its …
BACKGROUND CONTEXT: Degeneration and injuries of the intervertebral disc (IVD) result
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …
[图书][B] The Biomechanics of Back Pain-E-Book
Authored by experts of international renown, the new edition of The Biomechanics of Back
Pain forms a bridge between the latest research and the effective clinical management of …
Pain forms a bridge between the latest research and the effective clinical management of …
Immuno-modulatory effects of intervertebral disc cells
P Bermudez-Lekerika, KB Crump… - Frontiers in cell and …, 2022 - frontiersin.org
Low back pain is a highly prevalent, chronic, and costly medical condition predominantly
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …
A simple disc degeneration model induced by percutaneous needle puncture in the rat tail
B Han, K Zhu, F Li, Y Xiao, J Feng, Z Shi, M Lin, J Wang… - Spine, 2008 - journals.lww.com
Study Design. We evaluated the degenerative changes to rat tail vertebral discs induced by
percutaneous needle puncture, and we compared 2 puncture styles for the depth of needle …
percutaneous needle puncture, and we compared 2 puncture styles for the depth of needle …
MSU classification for herniated lumbar discs on MRI: toward developing objective criteria for surgical selection
LW Mysliwiec, J Cholewicki, MD Winkelpleck… - European spine …, 2010 - Springer
Abstract Currently, there are over 300,000 lumbar discectomies performed in the US
annually without an objective standard for patient selection. A prospective clinical outcome …
annually without an objective standard for patient selection. A prospective clinical outcome …
Contribution of the endplates to disc degeneration
AJ Fields, A Ballatori, EC Liebenberg… - Current molecular biology …, 2018 - Springer
Abstract Purpose of Review The endplates form the interface between the rigid vertebral
bodies and compliant intervertebral discs. Proper endplate function involves a balance …
bodies and compliant intervertebral discs. Proper endplate function involves a balance …