It is preferred that topically administered drugs act either dermally or transdermally. For that
reason they have to penetrate into the deeper skin layers or permeate the skin. The …

Context: Ever since the discovery of cyclodextrins, a family of cyclic oligosaccharides based
on α (1→ 4) linkage among glucopyranose subunits, these versatile supramolecular hosts …

The versatile pharmaceutical material cyclodextrin's (CDs) are classified into hydrophilic,
hydrophobic, and ionic derivatives. By the early 1950s the basic physicochemical …

Curcumin (CUR) has various pharmacological effects, but its extensive first-pass metabolism
and short elimination half-life limit its bioavailability. Therefore, transdermal application has …

Objectives Cyclodextrins are useful solubilizing excipients that have gained currency in the
formulator's armamentarium based on their ability to temporarily camouflage undesirable …

Cyclodextrins have proven themselves to be useful functional excipients. Cyclodextrin
derivatives can be hydrophilic or relatively lipophilic based on their substitution and these …

Enhancement strategies are necessary to improve the dermal/transdermal bioavailability of
drugs applied to the skin due to its amazing barrier, the stratum corneum. Strategies to …

Cyclodextrins (CDs) are cyclic oligosaccharides able to improve drug water solubility and
stability by forming CD/drug inclusion complexes. To further increase drug entrapment and …

Purpose Rheumatoid arthritis is an autoimmune disorder that directly affects joints. However,
other body organs including heart, eyes, skin, blood vessels and lungs may also be affected …

Cyclodextrins are promising, but using them as an excipients can sometimes be difficult. The
aim of this review is to summarize the results of recent studies on the application of parent …