In basic research, testing of oral fluid specimens by real-time quantitative polymerase chain
reaction (qPCR) has been used to evaluate changes in gene expression levels following …

Because quantitative reverse transcription PCR (RT-qPCR) gene expression data are
compositional, amounts of quantified RNAs must be normalized using reference genes …

Pseudogenes are duplicated or retrotransposed DNA sequences of native functional genes.
Amplification of pseudogenes along with gene of interest often produces false positive …

It is difficult to identify reliable reference genes for transcriptomic analyses in biofluids such
as saliva. This situation is particularly relevant for the newborn population, where rapid …

Background The underlying molecular mechanisms responsible for the etiology of autism
and its sex-biased prevalence remain largely elusive. We have previously shown that …

Chronic pain is a highly prevalent and costly issue that often emerges during childhood or
adolescence and persists into adulthood. Adverse childhood experiences (ACEs) increase …

Autism spectrum disorders (ASD) are strikingly more prevalent in males, but the molecular
mechanisms responsible for ASD sex-differential risk are poorly understood. Abnormally …

Cette étude pilote vise à développer une méthode d'analyse intégrative qui permet
d'augmenter le taux de réussite du diagnostic clinique des mutations génétiques rares. De …

The underlying molecular mechanisms responsible for the etiology of autism and its sex-
biased prevalence remain largely elusive. Abnormally shortened telomeres have recently …

The field of genetics encompasses genomics, transcriptomics and proteomics and entails
understanding the role of organisms' genes. These three omes along with numerous …