p38 MAPK signaling in osteoblast differentiation
E Rodríguez-Carballo, B Gámez… - Frontiers in cell and …, 2016 - frontiersin.org
The skeleton is a highly dynamic tissue whose structure relies on the balance between bone
deposition and resorption. This equilibrium, which depends on osteoblast and osteoclast …
deposition and resorption. This equilibrium, which depends on osteoblast and osteoclast …
Cellular signalling and photobiomodulation in chronic wound repair
TS Leyane, SW Jere, NN Houreld - International Journal of Molecular …, 2021 - mdpi.com
Photobiomodulation (PBM) imparts therapeutically significant benefits in the healing of
chronic wounds. Chronic wounds develop when the stages of wound healing fail to progress …
chronic wounds. Chronic wounds develop when the stages of wound healing fail to progress …
Human mesenchymal stem cell derived exosomes enhance cell‐free bone regeneration by altering their miRNAs profiles
Implantation of stem cells for tissue regeneration faces significant challenges such as
immune rejection and teratoma formation. Cell‐free tissue regeneration thus has a potential …
immune rejection and teratoma formation. Cell‐free tissue regeneration thus has a potential …
[HTML][HTML] Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities
Y Liu, C Wang, G Wang, Y Sun, Z Deng, L Chen… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: Osteoporosis is a severe bone disorder that is a threat to our aging population.
Excessive osteoclast formation and bone resorption lead to changes in trabecular bone …
Excessive osteoclast formation and bone resorption lead to changes in trabecular bone …
[HTML][HTML] Irisin as an agent for protecting against osteoporosis: A review of the current mechanisms and pathways
Background Osteoporosis is recognized as a skeletal disorder characterized by diminished
bone tissue quality and density. Regular physical exercise is widely acknowledged to …
bone tissue quality and density. Regular physical exercise is widely acknowledged to …
[HTML][HTML] Anti-inflammatory effect and potential mechanism of betulinic acid on λ-carrageenan-induced paw edema in mice
Z Ou, J Zhao, L Zhu, L Huang, Y Ma, C Ma… - Biomedicine & …, 2019 - Elsevier
Abstract λ-Carrageenan (Carr), a seaweed polysaccharide, is used as a proinflammatory
agent in research. Betulinic acid (BA), a naturally occurring pentacyclic triterpenoid, exerts …
agent in research. Betulinic acid (BA), a naturally occurring pentacyclic triterpenoid, exerts …
Identification and integrated analysis of differentially expressed lncRNAs and circRNAs reveal the potential ceRNA networks during PDLSC osteogenic differentiation
X Gu, M Li, Y Jin, D Liu, F Wei - BMC genetics, 2017 - Springer
Background Researchers have been exploring the molecular mechanisms underlying the
control of periodontal ligament stem cell (PDLSC) osteogenic differentiation. Recently, long …
control of periodontal ligament stem cell (PDLSC) osteogenic differentiation. Recently, long …
[HTML][HTML] Magnesium-containing bioceramics stimulate exosomal miR-196a-5p secretion to promote senescent osteogenesis through targeting Hoxa7/MAPK signaling …
L Qi, X Fang, J Yan, C Pan, W Ge, J Wang, SGF Shen… - Bioactive Materials, 2024 - Elsevier
Stem cell senescence is characterized by progressive functional dysfunction and secretory
phenotypic changes including decreased proliferation, dysfunction of osteogenic and …
phenotypic changes including decreased proliferation, dysfunction of osteogenic and …
[HTML][HTML] Long-term BPA exposure leads to bone malformation and abnormal expression of MAPK/Wnt/FoxO signaling pathway genes in zebrafish offspring
Z Zhu, J Wang, Q Cao, S Liu, W Wei, H Yang… - Ecotoxicology and …, 2022 - Elsevier
Bisphenol A (BPA) is one of the world's most widely used plasticizer, and its hazardous
impacts have been well studied. However, few studies focused on the effects of parental …
impacts have been well studied. However, few studies focused on the effects of parental …
A novel RANKL‐targeted flavonoid glycoside prevents osteoporosis through inhibiting NFATc1 and reactive oxygen species
G Hong, Z Chen, X Han, L Zhou, F Pang… - Clinical and …, 2021 - Wiley Online Library
Background and purpose Osteoporosis is characterized by excessive bone resorption due
to enhanced osteoclast activation. Stimulation of nuclear factor of activated T cells 1 …
to enhanced osteoclast activation. Stimulation of nuclear factor of activated T cells 1 …