Leishmaniasis is a parasitic, widespread, and neglected disease that affects more than 90
countries in the world. More than 20 Leishmania species cause different forms of …

The coordinating role of nuclear factor erythroid-2-related factor 2 (Nrf2) in cellular function
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …

The leishmaniases are diseases caused by pathogenic protozoan parasites of the genus
Leishmania. Infections are initiated when a sand fly vector inoculates Leishmania parasites …

Parasites of the Leishmania genus are the causative agents of leishmaniasis in humans, a
disease that affects more than 12 million people worldwide. These parasites replicate …

Leishmaniasis is a neglected tropical disease that affects about 350 million individuals
worldwide. The protozoan parasite has a relatively simple life cycle with two principal …

Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

Leishmaniasis remains a major public health problem worldwide and is classified as
Category I by the TDR/WHO, mainly due to the absence of control. Many experimental …

Cutaneous leishmaniasis affects millions of people around the world. Several species of
Leishmania infect mouse strains, and murine models closely reproduce the cutaneous …

Lifelong persistence after clinical cure of the primary infection is a characteristic feature of
many intracellular pathogens, including viruses, bacteria and protozoa. The underlying …

Leishmania parasites are able to secure their survival and propagation within their host by
altering signalling pathways involved in the ability of macrophages to kill pathogens or to …