Challenges and advances in clinical applications of mesenchymal stromal cells
T Zhou, Z Yuan, J Weng, D Pei, X Du, C He… - Journal of hematology & …, 2021 - Springer
Mesenchymal stromal cells (MSCs), also known as mesenchymal stem cells, have been
intensely investigated for clinical applications within the last decades. However, the majority …
intensely investigated for clinical applications within the last decades. However, the majority …
Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking
DE Murphy, OG de Jong, M Brouwer… - … & molecular medicine, 2019 - nature.com
Extracellular vesicles (EVs) are increasingly being recognized as mediators of intercellular
signaling via the delivery of effector molecules. Interestingly, certain types of EVs are also …
signaling via the delivery of effector molecules. Interestingly, certain types of EVs are also …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
[HTML][HTML] Mesenchymal stem cell-derived exosomes as a nanotherapeutic agent for amelioration of inflammation-induced astrocyte alterations in mice
P Xian, Y Hei, R Wang, T Wang, J Yang, J Li, Z Di… - Theranostics, 2019 - ncbi.nlm.nih.gov
Mesenchymal stem cell-derived exosomes (MSC-Exo) have robust anti-inflammatory effects
in the treatment of neurological diseases such as epilepsy, stroke, or traumatic brain injury …
in the treatment of neurological diseases such as epilepsy, stroke, or traumatic brain injury …
Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
Paracrine and endocrine roles have increasingly been ascribed to extracellular vesicles
(EVs) generated by multicellular organisms. Central to the biogenesis, content, and function …
(EVs) generated by multicellular organisms. Central to the biogenesis, content, and function …
The in vivo fate and targeting engineering of crossover vesicle-based gene delivery system
XC Jiang, T Zhang, JQ Gao - Advanced drug delivery reviews, 2022 - Elsevier
Exosomes and biomimetic vesicles are widely used for gene delivery because of their
excellent gene loading capacity and stability and their natural targeting delivery potential …
excellent gene loading capacity and stability and their natural targeting delivery potential …
Extracellular vesicles as delivery systems at nano-/micro-scale
Extracellular vesicles (EVs) have shown significant promises as nano-/micro-size carriers in
drug delivery and bioimaging. With more characteristics of EVs explored through …
drug delivery and bioimaging. With more characteristics of EVs explored through …
[HTML][HTML] Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design
Extracellular vesicles (EVs) are submicron cell-secreted structures containing proteins,
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …
Exosomal miR-21a-5p mediates cardioprotection by mesenchymal stem cells
KM Luther, L Haar, M McGuinness, Y Wang… - Journal of molecular and …, 2018 - Elsevier
Though experimental, stem cell transplantation has the potential to improve the condition of
the heart after myocardial infarction. It does so by reducing infarct size and inducing repair of …
the heart after myocardial infarction. It does so by reducing infarct size and inducing repair of …