Exosomes as mediators of intercellular crosstalk in metabolism
Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …
Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
The clinical potential of circulating microRNAs in obesity
C Ji, X Guo - Nature Reviews Endocrinology, 2019 - nature.com
Obesity is a complex condition that is characterized by excessive fat accumulation, which
can lead to the development of metabolic disorders, such as type 2 diabetes mellitus …
can lead to the development of metabolic disorders, such as type 2 diabetes mellitus …
Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …
miRNA signatures of insulin resistance in obesity
Objective Extracellular microRNAs (miRNAs) represent functional biomarkers for obesity
and related disorders; this study investigated plasma miRNAs in insulin resistance …
and related disorders; this study investigated plasma miRNAs in insulin resistance …
MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy
K Ait-Aissa, QM Nguyen, M Gabani, A Kassan… - Cardiovascular …, 2020 - Springer
The endothelium plays a pivotal role in maintaining vascular health. Obesity is a global
epidemic that has seen dramatic increases in both adult and pediatric populations. Obesity …
epidemic that has seen dramatic increases in both adult and pediatric populations. Obesity …
Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD
J Latorre, JM Moreno-Navarrete, JM Mercader… - International journal of …, 2017 - nature.com
Results: In the discovery sample, 14 miRNAs were associated with NAFLD. Analyses in the
extended sample confirmed decreased miR-139-5p, miR-30b-5p, miR-122-5p and miR …
extended sample confirmed decreased miR-139-5p, miR-30b-5p, miR-122-5p and miR …
Circulating microRNAs as potential biomarkers in non-alcoholic fatty liver disease and hepatocellular carcinoma
MB Afonso, PM Rodrigues, AL Simao… - Journal of clinical …, 2016 - mdpi.com
Obesity and metabolic syndrome are growing epidemics worldwide and greatly responsible
for many liver diseases, including nonalcoholic fatty liver disease (NAFLD). NAFLD often …
for many liver diseases, including nonalcoholic fatty liver disease (NAFLD). NAFLD often …
MicroRNA and adipogenesis
AB Engin - Obesity and lipotoxicity, 2017 - Springer
In obesity, the process of adipogenesis largely determines the number of adipocytes in body
fat depots. Adipogenesis is regulated by several adipocyte-selective microRNAs (miRNAs) …
fat depots. Adipogenesis is regulated by several adipocyte-selective microRNAs (miRNAs) …
Methods and novel technology for microRNA quantification in colorectal cancer screening
The screening and diagnosis of colorectal cancer (CRC) currently relies heavily on invasive
endoscopic techniques as well as imaging and antigen detection tools. More accessible and …
endoscopic techniques as well as imaging and antigen detection tools. More accessible and …