Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause
of cancer-related mortality rates worldwide. Although modern research was able to shed …

Uveal melanoma (UM) and retinoblastoma (RB), which cause blindness and even death,
are the most frequently observed primary intraocular malignancies in adults and children …

Curcumin (CUR), a major bioactive polyphenolic component from turmeric curry, Curcuma
longa, has been shown to be a potent anti-cancer phytochemical with well-established anti …

Epigenetic mechanisms are essential for normal development and maintenance of tissue-
specific gene expression patterns in mammals. Disruption of epigenetic processes can lead …

Apoptosis is a cell death programme primordial to cellular homeostasis efficiency. This
normal cell suicide program is the result of the activation of a cascade of events in response …

DNA methyltransferases (DNMTs) catalyze the methylation at cytosine-C5 mainly in a CpG
dinucleotide context. Although DNA methylation is essential for fundamental processes like …

Retinoblastoma is a rare type of eye cancer of the retina that commonly occurs in early
childhood and mostly affects the children before the age of 5. It occurs due to the mutations …

The phosphoinositide 3-kinase (PI3K)/v-akt murine thymoma (AKT) viral oncogene pathway
is involved in regulating the signaling of multiple biological processes such as apoptosis …

Background: Colorectal cancer (CRC) is a highly widespread malignancy and ranks as the
second most common cause of cancer-related mortality. Objective: Cancer patients …

Background Multiple myeloma (MM) is a malignant plasma cell disease with a poor survival,
characterized by the accumulation of myeloma cells (MMCs) within the bone marrow …