Abstract Silence information regulator 1 (SIRT1), a member of the sirtuin family, targets
histones and many non-histone proteins and participates in various physiological functions …

Obesity is a chronic disease caused by an excess of adipose tissue that may impair health
by altering the functionality of various organs, including the lungs. Excessive deposition of …

Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin
resistance, mitochondrial dysfunction, inflammation, and oxidative stress. As a group of …

Background and Aims Sirtuin 2 (SIRT2), an NAD+‐dependent deacetylase, is involved in
various cellular processes regulating metabolic homeostasis and inflammatory responses; …

Abstract Sirtuin 2 (SIRT2) belongs to the sirtuins family. It exists in many tissues and organs
of the human body and regulates a wide range of biological functions. Studies have found …

Ketone bodies (KBs) and Sirtuin-1 (SIRT1) have received increasing attention over the past
two decades given their pivotal function in a variety of biological contexts, including …

Aim Over the last decades, the shift in age distribution towards older ages and the
progressive ageing which has occurred in most populations have been paralleled by a …

The way by which subcutaneous adipose tissue (SAT) expands and undergoes remodeling
by storing excess lipids through expansion of adipocytes (hypertrophy) or recruitment of new …

Obesity is one of the biggest public health concerns identified by an increase in adipose
tissue mass as a result of adipocyte hypertrophy and hyperplasia. Pertaining to the …

Adipose tissue is an important endocrine organ that regulates metabolism, immune
response and aging in mammals. Healthy adipocytes promote tissue homeostasis and …