Digital ulcers (DUs) are a common visible manifestation of the progressive vascular disease
that characterizes the SSc disease process. DUs not only impact significantly on patients' …

Objective. Digital vasculopathy (comprising RP, digital ulceration and critical digital
ischaemia) is responsible for much of the pain and disability experienced by patients with …

Musculoskeletal (MSK) involvement of the hands is a significant source of morbidity,
impacting on quality of life in patients with systemic sclerosis (SSc). MSK complications are …

Objectives It is suggested that exercise can improve the vascular function and quality of life
(QoL) in people with systemic sclerosis (SSc), potentially offering clinical benefits to this …

Abstract Background: Digital ulcers (DUs) in systemic sclerosis (SSc) result from recurrent
Raynaud's phenomenon (RP) and microtrauma with high impact on quality of life. Medical …

Objectives Critical digital ischemia is a rare, but serious complication of systemic sclerosis
(SSc) and is not always due solely to the non-inflammatory angiopathy that characterizes the …

Vascular disease is a cardinal feature within the complex pathobiology of systemic sclerosis
(SSc). 1–3 Scleroderma renal crisis (SRC) and digital ulcers (DUs) share common …

Digital ulcers (DU) are one of the most common complication of Systemic Sclerosis (SSc)-
related vasculopathy and represent an important burden for the patients as well as for the …

The hand and wrist are commonly involved in rheumatic conditions, particularly rheumatoid
arthritis and other systemic connective tissue diseases. With spondyloarthritis, hand and …

Digital ulcers are a serious, recurrent complication in patients with systemic sclerosis. They
are often slow to heal and exquisitely painful. Local wound care, such as debridement of the …