Gut microbiota and immune responses

L Dong, J Xie, Y Wang, D Zuo - Gut Microbiota and Pathogenesis of Organ …, 2020 - Springer
The gut microbiota consists of a dynamic multispecies community living within a particular
niche in a mutual synergy with the host organism. Recent findings have revealed roles for …

Mutagenesis on a complex mouse genetic background by site-specific nucleases

B Davies, L Trelfa, VS Rashbrook, E Drydale… - Transgenic …, 2024 - Springer
Mouse models with complex genetic backgrounds are increasingly used in preclinical
research to accurately model human disease and to enable temporal and cell-specific …

The type 1 diabetes candidate gene Dexi does not affect disease risk in the nonobese diabetic mouse model

JM Nieves-Bonilla, B Kiaf, C Schuster, S Kissler - Genes & Immunity, 2020 - nature.com
Genome-wide association studies have implicated more than 50 genomic regions in type 1
diabetes (T1D). A T1D region at chromosome 16p13. 13 includes the candidate genes …

Functional Immunogenetics of Two GWAS Genes in Autoimmunity

JM Nieves-Bonilla - 2020 - search.proquest.com
Abstract Type I diabetes (T1D) is a chronic T cell-mediated autoimmune disease that results
in the destruction of insulin producing pancreatic β cells. More than 50 genomic regions …