Reactive oxygen species (ROS) are products of normal metabolism and xenobiotic
exposure, and depending on their concentration, ROS can be beneficial or harmful to cells …

Apoptosis or programmed cell death represents a physiologically conserved mechanism of
cell death that is pivotal in normal development and tissue homeostasis in all organisms. As …

The epidemiology of infectious causes of meningitis in sub-Saharan Africa is not well
understood, and a common cause of meningitis in this region, Mycobacterium tuberculosis …

Reactive oxygen species (ROS) play a key role in promoting mitochondrial cytochrome c
release and induction of apoptosis. ROS induce dissociation of cytochrome c from …

Increasing evidence suggests that mitochondrial dysfunction and oxidative stress play a
crucial role in the majority of neurodegenerative diseases. Mitochondria are a major source …

Cellular oxidative injury has been implicated in aging and a wide array of clinical disorders
including ischemia-reperfusion injury; neurodegenerative diseases; diabetes; inflammatory …

Apoptosis mediates the precise and programmed natural death of neurons and is a
physiologically important process in neurogenesis during maturation of the central nervous …

In cerebral circulation, epileptic seizures associated with excessive release of the excitatory
neurotransmitter glutamate cause endothelial injury. Heme oxygenase (HO), which …

The dipyridyl herbicide paraquat induces oxidative stress in cells and is implicated in adult
neurodegenerative diseases. However, less is known about paraquat toxicity in early stages …

Fatty acid has been reported to be associated with cardiovascular diseases and cancer, but
the possible mechanism remains unclear. Here, we reported a novel mechanism for the …