Recent progress in the synthesis of furan

DX Duc - Mini-Reviews in Organic Chemistry, 2019 - ingentaconnect.com
Furans are five-membered aromatic heterocycles containing one oxygen atom that are
important building blocks in organic chemistry, but also as natural products found in various …

Importance of Baylis-Hillman adducts in modern drug discovery

TN Reddy, VJ Rao - Tetrahedron letters, 2018 - Elsevier
Abstract The Baylis-Hillman (BH) reaction plays a fascinating role in the field of synthetic and
medicinal chemistry. BH adducts and their derivatives have been used as crucial synthons …

Odorless isocyanide chemistry: one-pot synthesis of heterocycles via the Passerini and postmodification tandem reaction based on the in situ capture of isocyanides

N Liu, F Chao, MG Liu, NY Huang, K Zou… - The Journal of organic …, 2019 - ACS Publications
This paper reports the tandem reaction strategy of the Passerini/Staudinger/aza-Wittig
reaction based on the in situ capture of isocyanides. According to this strategy, isocyanides …

Bridged [2.2. 1] bicyclic phosphine oxide facilitates catalytic γ-umpolung addition–Wittig olefination

K Zhang, L Cai, Z Yang, KN Houk, O Kwon - Chemical science, 2018 - pubs.rsc.org
A novel bridged [2.2. 1] bicyclic phosphine oxide, devised to circumvent the waste
generation and burdens of purification that are typical of reactions driven by the generation …

Tandem reaction strategy of the Passerini/Wittig reaction based on the in situ capture of isocyanides: One-pot synthesis of heterocycles

MG Liu, N Liu, WH Xu, L Wang - Tetrahedron, 2019 - Elsevier
This paper reports the tandem reaction strategy of the Passerini/Wittig reaction based on the
in situ capture of isocyanides. According to this strategy, plenty of isocyanides have been …

Isocyano(triphenylphosphoranylidene)acetates: Key to the One-Pot Synthesis of Oxazolo[4,5-c]quinoline Derivatives via a Sequential Ugi/Wittig/aza-Wittig Cyclization …

ZL Ren, WT Lu, S Cai, MM Xiao, YF Yuan… - The Journal of …, 2019 - ACS Publications
A one-pot novel strategy is described for the construction of various oxazolo [4, 5-c]
quinoline derivatives starting from the isocyano (triphenylphosphoranylidene) acetates …

C (sp2)–H Functionalization of Imidazole at the C2-and C4-Position via Palladium-Catalyzed Isocyanide Insertion Leading to Indeno [1, 2-d] imidazole and Imidazo [1 …

ZL Ren, S Cai, YY Liu, YQ Xie, D Yuan… - The Journal of …, 2020 - ACS Publications
An efficient strategy for the construction of fused imidazole derivatives through a palladium-
catalyzed isocyanide insertion reaction has been accomplished. The methodology provides …

Synthesis of 2-tetrazolyl-substituted 3-acylpyrroles via a sequential ugi-azide/Ag-catalyzed oxidative cycloisomerization reaction

HH Kong, HL Pan, MW Ding - The Journal of Organic Chemistry, 2018 - ACS Publications
A new efficient Ag-catalyed cascade cycloisomerization/aerobic oxidation reaction of a Ugi-
azide adduct for the preparation of 3-acylpyrroles using molecular oxygen as the terminal …

Synthesis of Polysubstituted Pyridine Derivatives via Sequential AlCl3‐Catalyzed Condensation/Aza‐Wittig/Isomerization Reactions and a Study of their Antifungal …

ZL Ren, L Su, S Cai, WT Lu, Y Qiao… - Asian Journal of …, 2019 - Wiley Online Library
A facile approach to access polysubstituted pyridine derivatives starting from Baylis‐Hillman
adducts is disclosed. The reactions proceeded smoothly by sequential AlCl3‐catalyzed …

Diastereoselective synthesis of multisubstituted isoindolines via sequential Ugi and aza-Michael addition reaction

ZR Guan, Q Wan, MW Ding - Tetrahedron, 2019 - Elsevier
A new efficient and diastereoselective synthesis of multisubstituted isoindolines with two
stereogenic centers via sequential Ugi/aza-Michael addition reaction was developed. Ugi …