HIV infection

LG Bekker, C Beyrer, N Mgodi, SR Lewin… - Nature Reviews …, 2023 - nature.com
The AIDS epidemic has been a global public health issue for more than 40 years and has
resulted in~ 40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted …

Evolving mechanisms and presentations of cardiovascular disease in people with HIV: implications for management

I Nazari, MJ Feinstein - Clinical microbiology reviews, 2024 - Am Soc Microbiol
People with HIV (PWH) are at elevated risk for cardiovascular diseases (CVDs), including
myocardial infarction, heart failure, and sudden cardiac death, among other CVD …

Metabolic-related outcomes after switching from tenofovir disoproxil fumarate to tenofovir alafenamide in adults with human immunodeficiency virus (HIV): a …

J Martínez-Sanz, S Serrano-Villar… - Clinical Infectious …, 2023 - academic.oup.com
Background Tenofovir alafenamide (TAF) has replaced tenofovir disoproxil fumarate (TDF)
in many clinical settings. However, concerns remain about potential metabolic complications …

Body weight increase and metabolic derangements after tenofovir disoproxil fumarate switch to tenofovir alafenamide in patients with chronic hepatitis B

PN Cheng, IC Feng, JJ Chen, HT Kuo… - Alimentary …, 2024 - Wiley Online Library
Background Lipid‐lowering effect was observed during treatment with tenofovir disoproxil
fumarate (TDF) for chronic hepatitis B (CHB). However, the metabolic features in patients …

Risk of dyslipidemia in chronic hepatitis B patients taking tenofovir alafenamide: a systematic review and meta-analysis

EG Hwang, EA Jung, JJ Yoo, SG Kim, YS Kim - Hepatology International, 2023 - Springer
Background The aim of this study was to demonstrate how tenofovir alafenamide (TAF) and
other hepatitis B treatment drugs differentially impact lipid profiles in chronic hepatitis B …

Metabolic syndrome among treatment‐naïve people living with and without HIV in Zambia and Zimbabwe: a cross‐sectional analysis

BV Chihota, A Mandiriri, T Shamu… - Journal of the …, 2022 - Wiley Online Library
Introduction Chronic viral replication has been linked to an increased risk of cardiovascular
and metabolic diseases in people living with HIV (PLWH), but few studies have evaluated …

Tolerability of bictegravir/tenofovir alafenamide/emtricitabine versus dolutegravir/lamivudine as maintenance therapy in a real-life setting

A Rocabert, B Borjabad, L Berrocal… - Journal of …, 2023 - academic.oup.com
Background While both the burden of therapy and the individual drugs in
bictegravir/tenofovir alafenamide/emtricitabine (BIC/TAF/FTC) and dolutegravir/lamivudine …

[HTML][HTML] Adipose tissue dysfunction and energy balance paradigms in people living with HIV

CER Bustamante, N Agarwal, AR Cox… - Endocrine …, 2024 - ncbi.nlm.nih.gov
Over the past 4 decades, the clinical care of people living with HIV (PLWH) evolved from
treatment of acute opportunistic infections to the management of chronic, noncommunicable …

[HTML][HTML] Bictegravir/tenofovir alafenamide/emtricitabine: A real-life experience in people living with HIV (PLWH)

A Gidari, S Benedetti, S Tordi, A Zoffoli… - Infectious Disease …, 2023 - mdpi.com
Background: Bictegravir (BIC), a recently introduced integrase inhibitor, is available in a
single tablet regimen with tenofovir alafenamide (TAF) and emtricitabine (FTC)(BIC-STR) …

Effectiveness and safety of tenofovir alafenamide in children and adolescents living with HIV: a systematic review

J O'Rourke, CL Townsend, E Milanzi… - Journal of the …, 2023 - Wiley Online Library
Introduction Tenofovir alafenamide (TAF) is approved for paediatric use in fixed‐dose
combination tablets, but efficacy and safety data in children are limited. We conducted a …