The chromosome 9p21 (Chr9p21) locus was discovered in 2007 by independent genome-
wide association studies for coronary artery disease. Since then, the locus has been …

Susceptibility to coronary artery disease (CAD) is claimed to be 40% to 60% inherited, but
until recently genetic risk factors predisposing to CAD have been elusive. Comprehensive …

Background High plasma HDL cholesterol is associated with reduced risk of myocardial
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes …

Coronary artery disease (CAD) has a significant genetic contribution that is incompletely
characterized. To complement genome-wide association (GWA) studies, we conducted a …

A new understanding of the genetic basis of coronary artery disease (CAD) has recently
emerged from genome-wide association (GWA) studies of common single-nucleotide …

Although over 30 common genetic susceptibility loci have been identified to be
independently associated with coronary artery disease (CAD) risk through genome-wide …

Coronary artery disease (CAD) including myocardial infarction (MI) is a common disease
and among the leading cause of death in the world. The onset of CAD depends on complex …

Background—Genome-wide association studies identified several single nucleotide
polymorphisms (SNP) associated with prevalent coronary heart disease (CHD), but less is …

Single nucleotide polymorphisms (SNPs) of non-coding RNA in the INK4 locus (ANRIL)
have been found to be associated with myocardial infarction (MI). However, the effect of …

Background Multiple genetic variants have been reliably associated with obesity-related
traits in Europeans, but little is known about their associations and interactions with lifestyle …