The arachidonic acid (AA) pathway plays a key role in cardiovascular biology,
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …

Breast cancer has seriously been threatening physical and mental health of women in the
world, and its morbidity and mortality also show clearly upward trend in China over time …

Myocardial infarction (MI) is one of the typical cardiovascular diseases, which persist as the
leading cause of death globally. Due to the poor regenerative capability of endogenous …

Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid by cytochrome P450
(CYP) epoxygenases, which include four regioisomers: 5, 6-EET, 8, 9-EET, 11, 12-EET, and …

The specific mechanism of pulmonary arterial hypertension (PAH) remains elusive. The
present study aimed to explore the underlying mechanism of PAH through the identity of …

Cytochrome P450 (CYP) enzymes are frequently referred to as the third pathway for the
metabolism of arachidonic acid. While it is true that these enzymes generate arachidonic …

Soluble epoxide hydrolase (sEH) degrades epoxides of fatty acids including
epoxyeicosatrienoic acid isomers (EETs), which are produced as metabolites of the …

Background: The beneficial effects of parasympathetic stimulation in pulmonary arterial
hypertension (PAH) have been reported. However, the specific mechanism has not been …

Myocardial infarction is still a life-threatening disease, even though its prognosis has been
improved through the development of percutaneous coronary intervention and …

Exercise training has been reported to ameliorate heart dysfunction in both humans and
animals after myocardial infarction (MI). Exercise-induced cardioprotective factors have …