Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Potential protective mechanisms of green tea polyphenol EGCG against COVID-19

Z Zhang, X Zhang, K Bi, Y He, W Yan, CS Yang… - Trends in food science & …, 2021 - Elsevier
Background The world is in the midst of the COVID-19 pandemic. In this comprehensive
review, we discuss the potential protective effects of (−)-epigallocatechin-3-gallate (EGCG) …

Promising antiviral activities of natural flavonoids against SARS-CoV-2 targets: systematic review

R Kaul, P Paul, S Kumar, D Büsselberg… - International journal of …, 2021 - mdpi.com
The ongoing COVID-19 pandemic, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became a globally leading public health concern over the past …

Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor

J Liu, BH Bodnar, F Meng, AI Khan, X Wang, S Saribas… - Cell & bioscience, 2021 - Springer
Background As the COVID-19 pandemic rages on, the new SARS-CoV-2 variants have
emerged in the different regions of the world. These newly emerged variants have mutations …

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

S Mehmood, M Maqsood, N Mahtab… - Journal of Food …, 2022 - Wiley Online Library
Epigallocatechin gallate (EGCG), a green tea catechin, has gained the attention of current
study due to its excellent health‐promoting effects. It possesses anti‐obesity, antimicrobial …

[HTML][HTML] Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry

D Zhang, S Hamdoun, R Chen, L Yang, CK Ip… - Pharmacological …, 2021 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) is caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), which enter the host cells through the interaction …

Chemico-biological aspects of (−)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: Current status and future …

R Sahadevan, S Singh, A Binoy… - Critical Reviews in Food …, 2023 - Taylor & Francis
Natural products have been a bedrock for drug discovery for decades.(−)-Epigallocatechin-3-
gallate (EGCG) is one of the widely studied natural polyphenolic compounds derived from …

Epigallocatechin gallate inhibits the uridylate-specific endoribonuclease Nsp15 and efficiently neutralizes the SARS-CoV-2 strain

S Hong, SH Seo, SJ Woo, Y Kwon… - Journal of Agricultural …, 2021 - ACS Publications
SARS-CoV-2, the coronavirus strain that initiated the COVID-19 pandemic, and its
subsequent variants present challenges to vaccine development and treatment. As the …

Epigallocatechin gallate (EGCG) attenuates severe acute respiratory coronavirus disease 2 (SARS-CoV-2) infection by blocking the interaction of SARS-CoV-2 spike …

T Ohishi, T Hishiki, MS Baig, S Rajpoot, U Saqib… - PLoS …, 2022 - journals.plos.org
The outbreak of the coronavirus disease 2019 caused by the severe acute respiratory
syndrome coronavirus 2 triggered a global pandemic where control is needed through …

Possible use of phytochemicals for recovery from COVID-19-induced anosmia and ageusia

S Koyama, K Kondo, R Ueha, H Kashiwadani… - International Journal of …, 2021 - mdpi.com
The year 2020 became the year of the outbreak of coronavirus, SARS-CoV-2, which
escalated into a worldwide pandemic and continued into 2021. One of the unique symptoms …