Human pythiosis is an infectious condition with high morbidity and mortality. The causative
agent is the oomycete microorganism Pythium insidiosum. The pathogen inhabits …

Despite their inherent toxicity and the acquired bacterial resistance that continuously
threaten their long-term clinical use, aminoglycosides (AGs) still remain valuable …

Background Pythium insidiosum is a parafungus that causes keratitis resembling fungal
keratitis. This study compares outcome in a large cohort of patients with P insidiosum …

Cationic amphiphiles derived from aminoglycosides (AGs) have been shown to exhibit
enhanced antimicrobial activity. Through the attachment of hydrophobic residues such as …

Efficacy and safety of three antibiotics (Linezolid-LZ, 0.2%; Azithromycin-AZ, 1%; Tigecycline-
TG, 1%) were determined in the treatment of Pythium insidiosum keratitis in rabbits. Infection …

Pythiosis is an emerging infectious disease caused by the aquatic oomycete Pythium
insidiosum, a fungal-like organism. It is believed that P. insidiosum's zoospores, its infected …

Purpose: To describe the previously unreported successful treatment of presumptive
Pythium keratitis (PK) with medical therapy alone. Methods: A 42-year-old female …

Pythiosis is a life-threatening infectious disease of humans and animals caused by the
oomycete microorganism Pythium insidiosum. The disease has been increasingly …

We have determined the in vitro activity of several antibacterial and antifungal drugs against
Pythium insidiosum using broth microdilution (BMD), disk diffusion, and Etest methods. The …

The present study investigated the in vitro and the in vivo interactions among azithromycin,
clarithromycin, minocycline, and tigecycline against Pythium insidiosum. In vitro …