Heart failure with preserved ejection fraction in the elderly: basic mechanisms and clinical considerations

K Gharagozloo, M Mehdizadeh, G Heckman… - Canadian Journal of …, 2024 - Elsevier
Heart failure (HF) with preserved ejection fraction (HFpEF) refers to a clinical condition in
which the signs of HF, such as pulmonary congestion, peripheral edema and increased …

Disturbed cardiac metabolism triggers atrial arrhythmogenesis in diabetes mellitus: Energy substrate alternate as a potential therapeutic intervention

B Lkhagva, TW Lee, YK Lin, YC Chen, CC Chung… - Cells, 2022 - mdpi.com
Atrial fibrillation (AF) is the most common type of sustained arrhythmia in diabetes mellitus
(DM). Its morbidity and mortality rates are high, and its prevalence will increase as the …

Metabolomics and Cardiovascular Risk in Patients with Heart Failure: A Systematic Review and Meta-Analysis

LS Neves, F Saraiva, R Ferreira… - International Journal of …, 2024 - mdpi.com
The associations of plasma metabolites with adverse cardiovascular (CV) outcomes are still
underexplored and may be useful in CV risk stratification. We performed a systematic review …

Leveraging metabolism for better outcomes in heart failure

YH Ng, YC Koay, FZ Marques, DM Kaye… - Cardiovascular …, 2024 - academic.oup.com
Whilst metabolic inflexibility and substrate constraint have been observed in heart failure for
many years, their exact causal role remains controversial. In parallel, many of our …

Tigecycline Opposes Bortezomib Effect on Myeloma Cells Decreasing Mitochondrial Reactive Oxygen Species Production

C Ramos-Acosta, L Huerta-Pantoja… - International Journal of …, 2024 - mdpi.com
Multiple myeloma is an incurable plasma cell malignancy. Most patients end up relapsing
and developing resistance to antineoplastic drugs, like bortezomib. Antibiotic tigecycline has …

Differences in Levels of Mitochondrial DNA Content at Various Stages of Canine Myxomatous Mitral Valve Disease

S Chirathanaphirom, P Chuammitri, W Pongkan… - Animals, 2023 - mdpi.com
Simple Summary Myxomatous mitral valve disease (MMVD) stands as a prevalent cardiac
ailment in the canine population, with the potential to culminate in heart failure. Within the …

Перенесенная острая декомпенсация сердечной недостаточности: структурно-функциональные изменения митохондрий

АА Гарганеева, ЕА Кужелева, ОВ Тукиш, КН Витт… - Кардиология, 2024 - lib.ossn.ru
Аннотация Цель. Сравнительная оценка структурных изменений митохондрий
кардиомиоцитов ушка правого предсердия и дыхательной функции митохондрий …