Y and W chromosome assemblies: approaches and discoveries
Hundreds of vertebrate genomes have been sequenced and assembled to date. However,
most sequencing projects have ignored the sex chromosomes unique to the heterogametic …
most sequencing projects have ignored the sex chromosomes unique to the heterogametic …
Gene drive: evolved and synthetic
A Burt, A Crisanti - ACS chemical biology, 2018 - ACS Publications
Drive is a process of accelerated inheritance from one generation to the next that allows
some genes to spread rapidly through populations even if they do not contribute to or …
some genes to spread rapidly through populations even if they do not contribute to or …
Assembly of the threespine stickleback Y chromosome reveals convergent signatures of sex chromosome evolution
Background Heteromorphic sex chromosomes have evolved repeatedly across diverse
species. Suppression of recombination between X and Y chromosomes leads to …
species. Suppression of recombination between X and Y chromosomes leads to …
Nix alone is sufficient to convert female Aedes aegypti into fertile males and myo-sex is needed for male flight
A Aryan, MAE Anderson, JK Biedler… - Proceedings of the …, 2020 - National Acad Sciences
A dominant male-determining locus (M-locus) establishes the male sex (M/m) in the yellow
fever mosquito, Aedes aegypti. Nix, a gene in the M-locus, was shown to be a male …
fever mosquito, Aedes aegypti. Nix, a gene in the M-locus, was shown to be a male …
De novo assembly of a young Drosophila Y chromosome using single-molecule sequencing and chromatin conformation capture
S Mahajan, KHC Wei, MJ Nalley, L Gibilisco… - PLoS …, 2018 - journals.plos.org
While short-read sequencing technology has resulted in a sharp increase in the number of
species with genome assemblies, these assemblies are typically highly fragmented …
species with genome assemblies, these assemblies are typically highly fragmented …
A maleness gene in the malaria mosquito Anopheles gambiae
E Krzywinska, NJ Dennison, GJ Lycett, J Krzywinski - Science, 2016 - science.org
The molecular pathways controlling gender are highly variable and have been identified in
only a few nonmammalian model species. In many insects, maleness is conferred by a Y …
only a few nonmammalian model species. In many insects, maleness is conferred by a Y …
Coalescent Analysis of Phylogenomic Data Confidently Resolves the Species Relationships in the Anopheles gambiae Species Complex
Y Thawornwattana, D Dalquen… - Molecular biology and …, 2018 - academic.oup.com
Deep coalescence and introgression make it challenging to infer phylogenetic relationships
among closely related species that arose through radiative speciation events. Despite …
among closely related species that arose through radiative speciation events. Despite …
Unique structure and positive selection promote the rapid divergence of Drosophila Y chromosomes
Y chromosomes across diverse species convergently evolve a gene-poor, heterochromatic
organization enriched for duplicated genes, LTR retrotransposons, and satellite DNA …
organization enriched for duplicated genes, LTR retrotransposons, and satellite DNA …
Advances and challenges in synthetic biology for mosquito control
Mosquito-borne illnesses represent a significant global health peril, resulting in
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …
Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases
Background Fusion of DNA methyltransferase domains to the nuclease-deficient clustered
regularly interspaced short palindromic repeat (CRISPR) associated protein 9 (dCas9) has …
regularly interspaced short palindromic repeat (CRISPR) associated protein 9 (dCas9) has …