Atropisomerism is a stereochemical behavior portrayed by three-dimensional molecules that
bear rotationally restricted σ bond. Akin to the well-represented point-chiral molecules …

Enantiomers, where chirality arises from restricted rotation around a single bond, are
atropisomers. Due to the unique nature of the origins of their chirality, synthetic strategies to …

This tutorial review provides a systematic overview of the available methodologies for the
atroposelective transformation of (heterobiaryl) biaryl precursors toward the synthesis of …

Conspectus Arising from the restricted rotation of a single bond caused by steric or
electronic effects, atropisomerism is one of the few fundamental categories for molecules to …

Although Suzuki–Miyaura cross-coupling is one of the most convenient and well-developed
cross-coupling reactions, its applications to the asymmetric version to deliver highly …

Highly efficient synthesis of axially chiral biaryl amines through cobalt‐catalyzed
atroposelective C− H arylation using easily accessible cobalt (II) salt and salicyloxazoline …

The stereocontrolled construction of C− C bonds remains one of the foremost challenges in
organic synthesis. At the heart of any chemical synthesis of a natural product or designed …

Catalytic dynamic kinetic asymmetric transformation (DyKAT) provides a powerful tool to
access chiral stereoisomers from racemic substrates. Such transformation has been widely …

Axially chiral biaryl scaffolds are essential structural units in chemistry. The asymmetric Pd-
catalyzed Suzuki–Miyaura cross-coupling reaction has been widely recognized as one of …

Axial chirality is a key feature of many important organic molecules, such as biologically
active compounds, stereogenic ligands and optically pure materials. Significant efforts in the …