Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …

Radiotherapy (RT) is a modality of oncologic treatment that can be used to treat
approximately 50% of all cancer patients either alone or in combination with other treatment …

Non-melanoma skin cancers (NMSCs) include basal cell carcinoma (BCC), squamous cell
carcinoma (SCC) and Merkel cell carcinoma (MCC). These neoplasms are highly diverse in …

Ethnopharmacological relevance With high mortality and morbidity rates, lung cancer (LC)
has become one of the major threats to human health. The treatment strategies for LC …

Hair follicle stem cells (HFSCs) are among the most widely available resources and most
frequently approved model systems used for studying adult stem cells. HFSCs are …

The Hedgehog (HH) signaling pathway plays important roles in gastrointestinal
carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death globally. The
cancer stem cells (CSCs) of HCC are responsible for tumor growth, invasion, metastasis …

Pancreatic ductal adenocarcinoma (PDAC) remains a leading cause of cancer related
death. The urgent need for effective therapies is highlighted by the lack of adequate …

Anthranilic acid and its analogues present a privileged profile as pharmacophores for the
rational development of pharmaceuticals deliberated for managing the pathophysiology and …

Purpose Meningiomas are the most frequently diagnosed intracranial neoplasms. Usually,
they are treated by surgical resection in curative intent. Radiotherapy and stereotactic …