Design, analysis, and pitfalls of clinical trials using ex situ liver machine perfusion: the international liver transplantation society consensus guidelines

PN Martins, MD Rizzari, D Ghinolfi, I Jochmans… - …, 2021 - journals.lww.com
Design, Analysis, and Pitfalls of Clinical Trials Using Ex S... : Transplantation Design, Analysis,
and Pitfalls of Clinical Trials Using Ex Situ Liver Machine Perfusion: The International Liver …

Does machine perfusion improve immediate and shortterm outcomes by enhancing graft function and recipient recovery after liver transplantation? A systematic …

A RamírezDel Val, J Guarrera, RJ Porte… - Clinical …, 2022 - Wiley Online Library
Background Recent evidence supports the use of machine perfusion technologies (MP) for
marginal liver grafts. Their effect on enhanced recovery, however, remains uncertain …

Transplantation of declined livers after normothermic perfusion

C Quintini, L Del Prete, A Simioni, L Del Angel, TD Uso… - Surgery, 2022 - Elsevier
Background The persistent shortage of liver allografts contributes to significant waitlist
mortality despite efforts to increase organ donation. Normothermic machine perfusion holds …

Perfusate enzymes and platelets indicate early allograft dysfunction after transplantation of normothermically preserved livers

A Weissenbacher, C Bogensperger, R Oberhuber… - …, 2022 - journals.lww.com
Background. Normothermic machine perfusion (NMP) has become a clinically established
tool to preserve livers in a near-physiological environment. However, little is known about …

[HTML][HTML] Normothermic machine perfusion (NMP) of the liver–current status and future perspectives

CJ van Beekum, TO Vilz, TR Glowka… - Annals of …, 2021 - ncbi.nlm.nih.gov
A shortage of available organs for liver transplantation has led transplant surgeons and
researchers to seek for innovative approaches in hepatoprotection and improvement of …

[HTML][HTML] A systematic review and meta-analysis of machine perfusion vs. static cold storage of liver allografts on liver transplantation outcomes: the future direction of …

J Jia, Y Nie, J Li, H Xie, L Zhou, J Yu… - Frontiers in medicine, 2020 - frontiersin.org
Background: Machine perfusion (MP) and static cold storage (CS) are two prevalent
methods for liver allograft preservation. However, the preferred method remains …

Liver transplant outcomes after ex vivo machine perfusion: a meta-analysis

B Liew, D Nasralla, S Iype, JM Pollok… - British Journal of …, 2021 - academic.oup.com
Background The pressure on liver-transplant programmes has expanded the usage of
extended-criteria allografts. Machine perfusion may be better than conventional static cold …

[HTML][HTML] The role of normothermic machine perfusion in liver transplantation

PN Martins, JE Buchwald, H Mergental… - International Journal of …, 2020 - Elsevier
To expand the donor pool of suitable organs for transplantation, there is an increased
interest in utilizing extended criteria donor grafts (ECD). Ex-situ machine perfusion has …

Ex vivo machine perfusion: current applications and future directions in liver transplantation

J Michelotto, JMGV Gassner, S Moosburner… - … archives of surgery, 2021 - Springer
Background Liver transplantation is the only curative treatment option for end-stage liver
disease; however, its use remains limited due to a shortage of suitable organs. In recent …

Normothermic machine perfusion systems: where do we go from here?

S López-Martínez, C Simón, X Santamaria - Transplantation, 2024 - journals.lww.com
Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating
physiological conditions such as body temperature. Recent advancements in NMP system …