Early islets and mesenchyme from an injured adult pancreas improve syngeneic engraftments and islet graft function in diabetic rats
V Tchokonte-Nana, JK Manda - Acta Histochemica, 2018 - Elsevier
A decrease in mass of isografts and a decline in islet function are major challenges in islet
transplantations. Despite this, transplantation of 84 h harvested pancreatic duct ligation …
transplantations. Despite this, transplantation of 84 h harvested pancreatic duct ligation …
Mesenchymal cells are required for epithelial duct cell-to-beta cell maturation and function in an injured adult pancreas in the rat
JK Manda, BJ Page, V Tchokonte-Nana - Acta Histochemica, 2017 - Elsevier
The islet, the endocrine portion of the pancreas− develops from an invagination of the
pancreatic duct epithelial cells (PDECs) into the surrounding tissue. The contact of the …
pancreatic duct epithelial cells (PDECs) into the surrounding tissue. The contact of the …
An in vitro study of mesenchyme–islet cell interactions in islet neogenesis: A model for tissue replacement therapy in diabetes mellitus
JK Manda - 2017 - scholar.sun.ac.za
Shortages of donor islets, immune rejection, and the need for life-long immuno-suppressors
remain the clinical challenges of islet transplantation in the treatment of diabetes mellitus. An …
remain the clinical challenges of islet transplantation in the treatment of diabetes mellitus. An …
[HTML][HTML] Immunohistochemical characterization of pancreatic duodenal homeobox protein-1, neurogenin-3, and insulin protein expressions in islet-mesenchymal cell …
JK Manda, V Tchokonte-Nana - Iranian Journal of Basic Medical …, 2018 - ncbi.nlm.nih.gov
Materials and Methods Healthy adult male Wistar rats (250-300 g) were obtained from the
Animal Unit of the Faculty of Medicine and Health Sciences, Stellenbosch University (Cape …
Animal Unit of the Faculty of Medicine and Health Sciences, Stellenbosch University (Cape …