The renin–angiotensin system (RAS) plays a major role in regulating electrolyte balance
and blood pressure. RAS has also been implicated in the regulation of inflammation …

Traumatic brain injury (TBI) is a major public health problem, with limited pharmacological
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …

Oxidative stress and neuronal apoptosis have been demonstrated to be key features in early
brain injury (EBI) after subarachnoid hemorrhage (SAH). Previous studies have indicated …

Background and Purpose Inflammation plays a key role in atherosclerosis. The protective
role of angiotensin 1–7 (Ang‐(1–7)) in vascular pathologies suggested the therapeutic use …

Angiotensins are a group of hormonal peptides and include angiotensin II and angiotensin 1–
7 produced by the renin angiotensin system. The biology, pharmacology and biochemistry of …

Acute inflammation can exacerbate brain injury after ischemic stroke. Beyond its well-
characterized role in calcium metabolism, it is becoming increasingly appreciated that the …

Cerebrovascular events, notably acute ischemic strokes (AIS), have been reported in the
setting of novel coronavirus disease (COVID-19) infection. Commonly regarded as …

The renin angiotensin system (RAS) consists of the systemic hormone system, critically
involved in regulation and homeostasis of normal physiological functions [ie blood pressure …

Thromboembolic stroke remains a major cause of neurological disability and death. Current
stroke treatments (aspirin, tissue plasminogen activator) are significantly limited by timing …

20-Hydroxyecdysone (20E) is a steroid hormone that plays a key role in insect development
through nuclear ecdysteroid receptors (EcR/RXR complex) and at least one membrane …