Role of neuroinflammation in neurodegeneration development
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy
C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing Research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …
Inflammation context in Alzheimer's disease, a relationship intricate to define
C Novoa, P Salazar, P Cisternas, C Gherardelli… - Biological Research, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …
Systematic review of miRNA as biomarkers in Alzheimer's disease
Currently there are 850,000 people with Alzheimer's disease in the UK, with an estimated
rise to 1.1 million by 2025. Alzheimer's disease is characterised by the accumulation of …
rise to 1.1 million by 2025. Alzheimer's disease is characterised by the accumulation of …
ApoE4: an emerging therapeutic target for Alzheimer's disease
M Safieh, AD Korczyn, DM Michaelson - BMC medicine, 2019 - Springer
Background The growing body of evidence indicating the heterogeneity of Alzheimer's
disease (AD), coupled with disappointing clinical studies directed at a fit-for-all therapy …
disease (AD), coupled with disappointing clinical studies directed at a fit-for-all therapy …
Epigenetics of Alzheimer's disease
There are currently no validated biomarkers which can be used to accurately diagnose
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
Deficiency in the ubiquitin conjugating enzyme UBE2A in Alzheimer's disease (AD) is linked to deficits in a natural circular miRNA-7 sponge (circRNA; ciRS-7)
Y Zhao, PN Alexandrov, V Jaber, WJ Lukiw - Genes, 2016 - mdpi.com
Our understanding of the highly specialized functions for small non-coding single-stranded
RNA (ssRNA) in the transcriptome of the human central nervous system (CNS) continues to …
RNA (ssRNA) in the transcriptome of the human central nervous system (CNS) continues to …
The epigenetics of aging and neurodegeneration
Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …
expression that do not involve changes in the genotype. Epigenetics is of increasing …
MicroRNAs in neuroinflammation: implications in disease pathogenesis, biomarker discovery and therapeutic applications
JA Slota, SA Booth - Non-coding RNA, 2019 - mdpi.com
The central nervous system can respond to threat via the induction of an inflammatory
response. Under normal circumstances this response is tightly controlled, however …
response. Under normal circumstances this response is tightly controlled, however …
MicroRNA-146a: a dominant, negative regulator of the innate immune response
MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that can play critical
roles as regulators of numerous pathways and biological processes including the immune …
roles as regulators of numerous pathways and biological processes including the immune …