▪ Abstract G protein–coupled receptors (GPRs) play a key role in controlling hormonal
regulation of numerous second-messenger pathways. However, following agonist activation …

Heptahelical G protein-coupled receptors are the most diverse and therapeutically important
family of receptors in the human genome. Ligand binding activates heterotrimeric G proteins …

We previously used a retroviral vector to mark clones in the postnatal rodent retina and
showed that at least two types of neurons and Müller glia can arise from a common …

Four genes expressed in the olfactory system of Drosophila melanogaster have been
identified by subtractive hybridization. Two of these genes, OS-E and OS-F, are related to …

Visual arrestin plays an important role in regulating light responsiveness via its ability to
specifically bind to the phosphorylated and light-activated form of rhodopsin. Previously, we …

In vertebrates, the arrestins are a family of four proteins that regulate the signaling and
trafficking of hundreds of different G-protein-coupled receptors (GPCRs). Arrestin homologs …

US8168380B2 - Methods and products for analyzing polymers - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents Methods and …

Signalling is one of the key processes in biological systems. It enables communication
within a single cell as well as among the many cells in higher organisms. Specialized …

Carotenoids are currently being intensely investigated regarding their potential to lower the
risk of chronic disease and vitamin A deficiency. Invertebrate models in which vitamin A …

Arrestins have been implicated in the regulation of many G protein-coupled receptor
signaling cascades. Mutations in two Drosophila photoreceptor-specific arrestin genes …