Bacterial pathogens as causative agents of infection constitute an alarming concern in the
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …

Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

Multidrug efflux systems display the ability to transport a variety of structurally unrelated
drugs from a cell and consequently are capable of conferring resistance to a diverse range …

One of the mechanisms that bacteria utilize to evade the toxic effects of antibiotics is the
active extrusion of structurally unrelated drugs from the cell. Both intrinsic and acquired …

To fulfill their nutritional requirement for iron, bacteria utilize various iron sources which
include the host proteins transferrin and lactoferrin, heme, and low molecular weight iron …

Foodborne illnesses caused by bacterial microorganisms are common worldwide and
constitute a serious public health concern. In particular, microorganisms belonging to the …

Multidrug resistance is a serious threat to public health. Proton motive force-driven
antiporters from the major facilitator superfamily (MFS) constitute a major group of multidrug …

Pathogenic microorganisms that are multidrug-resistant can pose severe clinical and public
health concerns. In particular, bacterial multidrug efflux transporters of the major facilitator …

ABSTRACT A multidrug efflux pump designated LmrS (lincomycin resistance protein of
Staphylococcus aureus), belonging to the major facilitator superfamily (MFS) of transporters …

The ESKAPEE bacterial pathogen Staphylococcus aureus has posed a serious public
health concern for centuries. Throughout its evolutionary course, S. aureus has developed …