Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature
astrocytes, but also an important component of the cytoskeleton in astrocytes during …

Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by
Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament …

A mechanism by which members of the ciliary neurotrophic factor (CNTF)–leukemia
inhibitory factor cytokine family regulate gliogenesis in the developing mammalian central …

With the goal of performing astrocyte‐specific modification of genes in the mouse, we have
generated a transgenic line expressing Cre recombinase under the control of the human …

Alexander disease is a rare disorder of the central nervous system of unknown etiology 1, 2.
Infants with Alexander disease develop a leukoencephalopathy with macrocephaly …

We have generated transgenic mice in which astrocytes are labeled by the enhanced green
fluorescent protein (EGFP) under the control of the human glial fibrillary acidic protein …

Changes in intermediate filament gene expression occur at key steps in the differentiation of
cell types in the mammalian CNS. Neuroepithelial stem cells express the intermediate …

Glial fibrillary acidic protein (GFAP) is an intermediate-filament protein expressed
abundantly and almost exclusively in astrocytes of the CNS. We are studying transcriptional …

Glial fibrillary acidic protein (GFAP) is the major intermediate filament protein in astrocytes,
one of the most abundant cell types in the vertebrate central nervous system (CNS) …

The hallmark response to injury or stress in the central nervous system (CNS) is an up-
regulation in astrocytes of intermediate filament proteins, highly stable structural …