Evolutionary constraint and innovation across hundreds of placental mammals
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …
Ground squirrels–experts in thermoregulatory adaptation
Ground squirrels exemplify one of the most extreme forms of mammalian hibernation and a
convenient model for studying its mechanisms. Their thermoregulatory system demonstrates …
convenient model for studying its mechanisms. Their thermoregulatory system demonstrates …
Liver transcriptome dynamics during hibernation are shaped by a shifting balance between transcription and RNA stability
Hibernators dramatically lower metabolism to save energy while fasting for months.
Prolonged fasting challenges metabolic homeostasis, yet small-bodied hibernators emerge …
Prolonged fasting challenges metabolic homeostasis, yet small-bodied hibernators emerge …
Comparative transcriptomics of the garden dormouse hypothalamus during hibernation
E Haugg, J Borner, G Stalder, A Kübber‐Heiss… - FEBS Open …, 2024 - Wiley Online Library
Torpor or heterothermy is an energy‐saving mechanism used by endotherms to overcome
harsh environmental conditions. During winter, the garden dormouse (Eliomys quercinus) …
harsh environmental conditions. During winter, the garden dormouse (Eliomys quercinus) …
Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor
E Haugg, J Borner, V Diedrich, A Herwig - FEBS Open Bio, 2022 - Wiley Online Library
The energy‐saving strategy of Djungarian hamsters (Phodopus sungorus, Cricetidae) to
overcome harsh environmental conditions comprises of behavioral, morphological, and …
overcome harsh environmental conditions comprises of behavioral, morphological, and …
Blood transcriptomics mirror regulatory mechanisms during hibernation—a comparative analysis of the Djungarian hamster with other mammalian species
VR Cuyutupa, D Moser, V Diedrich, Y Cheng… - … -European Journal of …, 2023 - Springer
Hibernation enables many species of the mammalian kingdom to overcome periods of harsh
environmental conditions. During this physically inactive state metabolic rate and body …
environmental conditions. During this physically inactive state metabolic rate and body …
Adrenal gene expression dynamics support hibernation in 13-lined ground squirrels
AE Gillen, LE Epperson, DJ Orlicky… - Physiological …, 2023 - journals.physiology.org
Hibernation is a natural model of extreme physiology in a mammal. Throughout winter, small
hibernators repeatedly undergo rapid, dramatic swings in body temperature, perfusion, and …
hibernators repeatedly undergo rapid, dramatic swings in body temperature, perfusion, and …
Numerous independent gains of torpor and hibernation across endotherms, linked with adaptation to diverse environments
Many endotherms from diverse taxonomic groups can respond to environmental changes
through dormancy, ie, by greatly reducing their energy expenditure for up to 24 hours (daily …
through dormancy, ie, by greatly reducing their energy expenditure for up to 24 hours (daily …
Ecology Meets Physiology: Phenotypic Plasticity and the Ability of Animals to Adjust to Changing Environmental Conditions
JP Hildebrandt - Physiologia, 2023 - mdpi.com
Hyperplasia and hypertrophy, or their counterparts hypoplasia and hypotrophy, are
elements of the adjustment of organ size and function in animals according to their needs …
elements of the adjustment of organ size and function in animals according to their needs …
Identification of conserved gene expression programs activated in multiple modes of torpor across vertebrate clades.
K Weir, N Vega, V Busa, B Sajdak, L Kallestad… - bioRxiv, 2023 - biorxiv.org
Torpor encompasses adaptations to diverse extreme environmental stressors such as
hibernation, aestivation, brumation, and daily torpor. Here we introduce StrokeofGenus, an …
hibernation, aestivation, brumation, and daily torpor. Here we introduce StrokeofGenus, an …