Drawbacks of artificial intelligence and their potential solutions in the healthcare sector

B Khan, H Fatima, A Qureshi, S Kumar… - Biomedical Materials & …, 2023 - Springer
Artificial intelligence (AI) has the potential to make substantial progress toward the goal of
making healthcare more personalized, predictive, preventative, and interactive. We believe …

Emerging role of ferroptosis in breast cancer: New dawn for overcoming tumor progression

S Sui, S Xu, D Pang - Pharmacology & therapeutics, 2022 - Elsevier
Breast cancer has become a serious threat to women's health. Cancer progression is mainly
derived from resistance to apoptosis induced by procedures or therapies. Therefore, new …

Development and characterisation of acquired radioresistant breast cancer cell lines

M Gray, AK Turnbull, C Ward, J Meehan… - Radiation …, 2019 - Springer
Background Radiotherapy plays an important role in the multimodal treatment of breast
cancer. The response of a breast tumour to radiation depends not only on its innate …

[HTML][HTML] Artificial intelligence in clinical health care applications

M Van Hartskamp, S Consoli, W Verhaegh… - Interactive journal of …, 2019 - i-jmr.org
The idea of artificial intelligence (AI) has a long history. It turned out, however, that reaching
intelligence at human levels is more complicated than originally anticipated. Currently, we …

Estrogen receptor pathway activity score to predict clinical response or resistance to neoadjuvant endocrine therapy in primary breast cancer

MA Inda, EJ Blok, PJK Kuppen, A Charehbili… - Molecular cancer …, 2020 - AACR
Endocrine therapy is important for management of patients with estrogen receptor (ER)–
positive breast cancer; however, positive ER staining does not reliably predict therapy …

Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways

GF van Wigcheren, J Cuenca-Escalona… - Journal of Biological …, 2023 - ASBMB
Imbalanced immune responses are a prominent hallmark of cancer and autoimmunity.
Myeloid cells can be overly suppressive, inhibiting protective immune responses or inactive …

Measurement of cellular immune response to viral infection and vaccination

W Bouwman, W Verhaegh, L Holtzer… - Frontiers in …, 2020 - frontiersin.org
Combined cellular and humoral host immune response determine the clinical course of a
viral infection and effectiveness of vaccination, but currently the cellular immune response …

Quantitative measurement of functional activity of the PI3K signaling pathway in cancer

A van de Stolpe - Cancers, 2019 - mdpi.com
The phosphoinositide 3-kinase (PI3K) growth factor signaling pathway plays an important
role in embryonic development and in many physiological processes, for example the …

RNA based approaches to profile oncogenic pathways from low quantity samples to drive precision oncology strategies

A Van De Stolpe, W Verhaegh, JY Blay, CX Ma… - Frontiers in …, 2021 - frontiersin.org
Precision treatment of cancer requires knowledge on active tumor driving signal
transduction pathways to select the optimal effective targeted treatment. Currently only a …

Oestrogen receptor pathway activity is associated with outcome in endometrial cancer

WJ van Weelden, LJM van der Putten, MA Inda… - British journal of …, 2020 - nature.com
Background Oestrogen receptor (ER) expression is a prognostic biomarker in endometrial
cancer (EC). However, expression does not provide information about the functional activity …