Toll-like receptors and thrombopoiesis
X Tang, Q Xu, S Yang, X Huang, L Wang… - International Journal of …, 2023 - mdpi.com
Platelets are the second most abundant blood component after red blood cells and can
participate in a variety of physiological and pathological functions. Beyond its traditional role …
participate in a variety of physiological and pathological functions. Beyond its traditional role …
The combination of machine learning and transcriptomics reveals a novel megakaryopoiesis inducer, MO-A, that promotes thrombopoiesis by activating FGF1/FGFR1 …
T Zhang, Q Mo, N Jiang, Y Wu, X Yang, W Chen… - European Journal of …, 2023 - Elsevier
Radiation-induced thrombocytopenia (RIT) occurs widely and causes high mortality and
morbidity in cancer patients who receive radiotherapy. However, specific drugs for treating …
morbidity in cancer patients who receive radiotherapy. However, specific drugs for treating …
Downregulation of XBP1s aggravates lipopolysaccharide-induced inflammation by promoting NF-κB and NLRP3 pathways' activation in goat endometrial epithelial …
K Gao, Y Yi, Z Xue, Z Wang, S Huang, B Zhang, P Lin… - Theriogenology, 2023 - Elsevier
After delivery, bacterial contamination and uterine tissue degeneration in animals can lead
to the development of uterine diseases, such as endometritis, accompanied by endoplasmic …
to the development of uterine diseases, such as endometritis, accompanied by endoplasmic …
Terpinen-4-ol Improves Lipopolysaccharide-Induced Macrophage Inflammation by Regulating Glutamine Metabolism
Y Liu, X Tang, H Zhang, L Zheng, P Lai, C Guo, J Ma… - Foods, 2024 - mdpi.com
Terpinen-4-ol (T-4-O) is an important component of tea tree oil and has anti-inflammatory
effects. Currently, there are very few studies on the mechanisms by which T-4-O improves …
effects. Currently, there are very few studies on the mechanisms by which T-4-O improves …
Fisetin modulates toll-like receptor-mediated innate antiviral response in Chikungunya virus-infected hepatocellular carcinoma Huh7 cells
In the chronic phase of chikungunya virus (CHIKV) infection, excessive inflammation
manifests as incapacitating joint pain and prolonged arthritis. Arthritis resulted from a large …
manifests as incapacitating joint pain and prolonged arthritis. Arthritis resulted from a large …
[HTML][HTML] Significance of TLR2 signaling during megakaryocyte development: regulatory cross-talk of miR-125b, cytokine induction, and MAPK pathway during dengue …
M Malleswarapu, N Kovuru, N Khan… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: Dengue is a viral infection endemic in more than 100 countries as per the WHO
reports with approximately 5.2 million patients worldwide that spreads from mosquitoes to …
reports with approximately 5.2 million patients worldwide that spreads from mosquitoes to …
Inhibition of the TLR4/NF-κB/TNF-α axis by TAK-242 or PDTC reduces central nervous system inflammation to alleviate lipopolysaccharide induced sickness …
P Tuo, Y Wang, W Chen, J Xie, Y Jie, J Liu, X Liu… - 2022 - researchsquare.com
Background: During the pathogenic microorganisms infection, animals will exhibit sickness
behaviors, yet there is a lack of sufficient research on the pathogenesis of sickness …
behaviors, yet there is a lack of sufficient research on the pathogenesis of sickness …