Certain morphological, physiological and molecular characteristics are shared by all
neurons. However, despite these similarities, neurons constitute the most diverse cell …

Cranial placodes are specialized regions of the ectoderm, which give rise to various sensory
ganglia and contribute to the pituitary gland and sensory organs of the vertebrate head …

During nervous system development, neurons extend axons along well-defined pathways.
The current understanding of axon pathfinding is based mainly on chemical signaling …

The development of single-cell RNA sequencing (scRNA-seq) has allowed high-resolution
analysis of cell-type diversity and transcriptional networks controlling cell-fate specification …

The molecular mechanisms mediating the retinogenic potential of multipotent retinal
progenitor cells (RPCs) are poorly defined. Prior to initiating retinogenesis, RPCs express a …

Understanding the molecular mechanisms by which distinct cell fate is determined during
organogenesis is a central issue in development and disease. Here, using conditional gene …

The vertebrate retina contains seven major neuronal and glial cell types in an
interconnected network that collects, processes and sends visual signals through the optic …

math5 is a murine orthologue of atonal, a bHLH proneural gene essential for the formation of
photoreceptors and chordotonal organs in Drosophila. The expression of math5 coincides …

Tissue mechanics is important for development; however, the spatio-temporal dynamics of in
vivo tissue stiffness is still poorly understood. We here developed tiv-AFM, combining time …

Mutation of the zebrafish lakritz (lak) locus completely eliminates the earliest-born retinal
cells, the ganglion cells (RGCs). Instead, excess amacrine, bipolar, and Müller glial cells are …