Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …

Oxidative stress is a normal phenomenon in the body. Under normal conditions, the
physiologically important intracellular levels of reactive oxygen species (ROS) are …

Cadmium (Cd) is a significant ecotoxic heavy metal that adversely affects all biological
processes of humans, animals and plants. Exposure to acute and chronic Cd damages …

Stroke is the second leading cause of death, after ischemic heart disease, and accounts for
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …

Abstract The Editors of the Journal of Alzheimer's Disease invited Professor Patrizia Mecocci
to contribute a review article focused on the importance and implications of her research on …

Stroke is one of the leading causes of mortality and morbidity, with astronomical financial
repercussions on health systems worldwide. Ischaemic stroke accounts for approximately 80 …

Oxidative stress is a phenomenon associated with pathogenetic mechanisms of several
diseases including atherosclerosis, neurodegenerative diseases, such as Alzheimer's and …

Adequate sleep is essential for normal brain function, especially during early life
developmental stages as postnatal brain maturation occurs during the critical period of …

The interplay between free radicals, antioxidants, and co-factors is important in maintaining
health, aging and age-related diseases. Free radicals induce oxidative stress, which is …

A family of detoxifying enzymes called aldehyde dehydrogenases (ALDHs) has been a
subject of recent interest, as its role in detoxifying aldehydes that accumulate through …