Quantitative magnetic resonance imaging of brain anatomy and in vivo histology
Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …
aims primarily at local image contrast. It provides specific physical parameters related to the …
[HTML][HTML] Myelin quantification with MRI: A systematic review of accuracy and reproducibility
CWJ van der Weijden, DV García, RJH Borra… - Neuroimage, 2021 - Elsevier
Objectives Currently, multiple sclerosis is treated with anti-inflammatory therapies, but these
treatments lack efficacy in progressive disease. New treatment strategies aim to repair …
treatments lack efficacy in progressive disease. New treatment strategies aim to repair …
So you want to image myelin using MRI: an overview and practical guide for myelin water imaging
Myelin water imaging (MWI) is an MRI imaging biomarker for myelin. This method can
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …
[HTML][HTML] An atlas for human brain myelin content throughout the adult life span
AV Dvorak, T Swift-LaPointe, IM Vavasour, LE Lee… - Scientific reports, 2021 - nature.com
Myelin water imaging is a quantitative neuroimaging technique that provides the myelin
water fraction (MWF), a metric highly specific to myelin content, and the intra-/extra-cellular …
water fraction (MWF), a metric highly specific to myelin content, and the intra-/extra-cellular …
Probing myelin content of the human brain with MRI: A review
Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …
with water between the wraps. The measurement of damage to the myelin sheaths, the …
[HTML][HTML] Insights into human cerebral white matter maturation and degeneration across the adult lifespan
White matter (WM) microstructural properties change across the adult lifespan and with
neuronal diseases. Understanding microstructural changes due to aging is paramount to …
neuronal diseases. Understanding microstructural changes due to aging is paramount to …
[HTML][HTML] Investigation of the association between cerebral iron content and myelin content in normative aging using quantitative magnetic resonance neuroimaging
Myelin loss and iron accumulation are cardinal features of aging and various
neurodegenerative diseases. Oligodendrocytes incorporate iron as a metabolic substrate for …
neurodegenerative diseases. Oligodendrocytes incorporate iron as a metabolic substrate for …
Adult brain aging investigated using BMC-mcDESPOT–based myelin water fraction imaging
The relationship between regional brain myelination and aging has been the subject of
intense study, with magnetic resonance imaging perhaps the most effective modality for …
intense study, with magnetic resonance imaging perhaps the most effective modality for …
[HTML][HTML] Estimating axon conduction velocity in vivo from microstructural MRI
The conduction velocity (CV) of action potentials along axons is a key neurophysiological
property central to neural communication. The ability to estimate CV in humans in vivo from …
property central to neural communication. The ability to estimate CV in humans in vivo from …