Müller cells in the healthy and diseased retina

A Bringmann, T Pannicke, J Grosche, M Francke… - Progress in retinal and …, 2006 - Elsevier
Müller glial cells span the entire thickness of the tissue, and ensheath all retinal neurons, in
vertebrate retinae of all species. This morphological relationship is reflected by a multitude …

Diabetic macular edema: pathogenesis and treatment

N Bhagat, RA Grigorian, A Tutela, MA Zarbin - Survey of ophthalmology, 2009 - Elsevier
Diabetic macular edema is a major cause of visual impairment. The pathogenesis of
macular edema appears to be multifactorial. Laser photocoagulation is the standard of care …

[HTML][HTML] Therapeutic targets of renin-angiotensin system in ocular disorders

R Choudhary, MS Kapoor, A Singh… - Journal of current …, 2017 - Elsevier
Purpose To review current literature on the renin-angiotensin system (RAS)-mediated
pathogenic mechanisms and therapeutic targets in ocular diseases. Methods A …

[HTML][HTML] Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways

CW Wong, TY Wong, CY Cheng, C Sabanayagam - Kidney international, 2014 - Elsevier
Chronic kidney disease is an emerging health problem worldwide. The eye shares striking
structural, developmental, and genetic pathways with the kidney, suggesting that kidney …

Neurodegenerative influence of oxidative stress in the retina of a murine model of diabetes

M Sasaki, Y Ozawa, T Kurihara, S Kubota, K Yuki… - Diabetologia, 2010 - Springer
Aims/hypothesis Diabetic retinopathy is a progressive neurodegenerative disease, but the
underlying mechanism is still obscure. Here, we focused on oxidative stress in the retina …

[HTML][HTML] Many faces of renin-angiotensin system-focus on eye

M Holappa, H Vapaatalo… - The open ophthalmology …, 2017 - ncbi.nlm.nih.gov
The renin-angiotensin system (RAS), that is known for its role in the regulation of blood
pressure as well as in fluid and electrolyte homeostasis, comprises dozens of angiotensin …

Angiotensin II and its receptor subtypes in the human retina

PS Senanayake, J Drazba, K Shadrach… - … & visual science, 2007 - iovs.arvojournals.org
purpose. To quantify and evaluate the distribution of angiotensin II (Ang II) and its receptors
in the human retina. methods. Donor eyes were obtained within 12 hours postmortem and …

[PDF][PDF] Role of Muller cells in retinal degenerations

A Bringmann, A Reichenbach - Front Biosci, 2001 - academia.edu
[Frontiers in Bioscience 6, e77-92, October 1, 2001] 77 ROLE OF MÜLLER CELLS IN RETINAL
DEGENERATIONS Andreas Bringmann and And Page 1 [Frontiers in Bioscience 6, e77-92 …

Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor–type integrins inhibits retinal neovascularization

HP Hammes, M Brownlee, A Jonczyk, A Sutter… - Nature medicine, 1996 - nature.com
Retinal neovascularization is a major cause of blindness in such disorders as retinopathy of
prematurity, proliferative diabetic retinopathy and senile macular degeneration. Because …

Involvement of Müller glial cells in epiretinal membrane formation

A Bringmann, P Wiedemann - Graefe's archive for clinical and …, 2009 - Springer
Background Proliferative retinopathies are considered to represent maladapted retinal
wound repair processes driven by growth factor-and cytokine-induced overstimulation of …