Annual Research Review: The role of the environment in the developmental psychopathology of autism spectrum condition
Background Although autism spectrum condition (ASC) is strongly genetic in origin,
accumulating evidence points to the critical roles of various environmental influences on its …
accumulating evidence points to the critical roles of various environmental influences on its …
Aromatase in the human brain
I Azcoitia, P Mendez… - … : clinical research and …, 2021 - liebertpub.com
The aromatase cytochrome P450 (P450arom) enzyme, or estrogen synthase, which is
coded by the CYP19A1 gene, is widely expressed in a subpopulation of excitatory and …
coded by the CYP19A1 gene, is widely expressed in a subpopulation of excitatory and …
[HTML][HTML] Retinoic acid-related orphan receptors (RORs): regulatory functions in immunity, development, circadian rhythm, and metabolism
DN Cook, HS Kang, AM Jetten - Nuclear receptor research, 2015 - ncbi.nlm.nih.gov
In this overview, we provide an update on recent progress made in understanding the
mechanisms of action, physiological functions, and roles in disease of retinoic acid related …
mechanisms of action, physiological functions, and roles in disease of retinoic acid related …
[HTML][HTML] Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions
S Thongkorn, S Kanlayaprasit, P Panjabud, T Saeliw… - Scientific Reports, 2021 - nature.com
Our recent study has shown that prenatal exposure to bisphenol A (BPA) altered the
expression of genes associated with autism spectrum disorder (ASD). In this study, we …
expression of genes associated with autism spectrum disorder (ASD). In this study, we …
[HTML][HTML] Understanding autism in the light of sex/gender
Autism has long been described as a predominantly male condition, with a widely cited
male: female ratio of 4 to 5: 1 [1]. Over the past two decades, we have witnessed a trend …
male: female ratio of 4 to 5: 1 [1]. Over the past two decades, we have witnessed a trend …
Vitamin A and vitamin D deficiencies exacerbate symptoms in children with autism spectrum disorders
M Guo, J Zhu, T Yang, X Lai, Y Lei, J Chen… - Nutritional …, 2019 - Taylor & Francis
Objectives: This study was designed to investigate the vitamin A (VA) and vitamin D (VD)
levels in children with autism spectrum disorders (ASD) and to determine whether co …
levels in children with autism spectrum disorders (ASD) and to determine whether co …
[HTML][HTML] Sex differences in brain plasticity: a new hypothesis for sex ratio bias in autism
Several observations support the hypothesis that differences in synaptic and regional
cerebral plasticity between the sexes account for the high ratio of males to females in autism …
cerebral plasticity between the sexes account for the high ratio of males to females in autism …
[HTML][HTML] Language impairments in ASD resulting from a failed domestication of the human brain
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders entailing
social and cognitive deficits, including marked problems with language. Numerous genes …
social and cognitive deficits, including marked problems with language. Numerous genes …
[HTML][HTML] Autism-related transcription factors underlying the sex-specific effects of prenatal bisphenol a exposure on transcriptome-interactome profiles in the offspring …
S Kanlayaprasit, S Thongkorn, P Panjabud… - International Journal of …, 2021 - mdpi.com
Bisphenol A (BPA) is an environmental risk factor for autism spectrum disorder (ASD). BPA
exposure dysregulates ASD-related genes in the hippocampus and neurological functions …
exposure dysregulates ASD-related genes in the hippocampus and neurological functions …
[HTML][HTML] Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism
VW Hu, T Sarachana, RM Sherrard, KM Kocher - Molecular autism, 2015 - Springer
Background Autism spectrum disorder (ASD) is a neurodevelopmental condition
characterized by significant impairment in reciprocal social interactions and communication …
characterized by significant impairment in reciprocal social interactions and communication …