Chronic kidney disease (CKD) affects over 850 million people globally, and there is an
urgent need to prevent its development and progression. During the last decade, new …

Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Mortality
and morbidity associated with DKD are increasing with the global prevalence of type 2 …

Glucagon-like peptide-1 receptor (GLP-1R) is a critical therapeutic target for type 2 diabetes
mellitus (T2DM). The GLP-1R cellular signaling mechanism relevant to insulin secretion and …

Diabetes is one of the leading causes of chronic kidney disease (CKD), and multiple
underlying mechanisms involved in pathogenesis of diabetic nephropathy (DN) have been …

Owing to the increasing prevalence of diabetic mellitus, diabetic kidney disease (DKD) is
presently the leading cause of chronic kidney disease and end‐stage renal disease …

Thanks to technical advances in the field of medical imaging, it is now possible to study key
features of renal anatomy and physiology, but so far poorly explored due to the inherent …

Urinary extracellular vesicles (uEV) are a largely unexplored source of kidney-derived
mRNAs with potential to serve as a liquid kidney biopsy. We assessed∼ 200 uEV mRNA …

Aim Tissue hypoxia is an early key feature of acute kidney injury. Assessment of renal
oxygenation using magnetic resonance imaging (MRI) markers T2 and T2* enables insights …

Renal magnetic resonance imaging (MRI) techniques are currently in vogue, as they provide
in vivo information on renal volume, function, metabolism, perfusion, oxygenation, and …

Diabetic nephropathy (DN) and non-diabetic renal diseases (NDRD) represent intricate
challenges in diagnosis and treatment within the context of the global diabetes epidemic. As …