Cellular origins of dsRNA, their recognition and consequences
YG Chen, S Hur - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Double-stranded RNA (dsRNA) is associated with most viral infections—it either constitutes
the viral genome (in the case of dsRNA viruses) or is generated in host cells during viral …
the viral genome (in the case of dsRNA viruses) or is generated in host cells during viral …
Small RNAs in bacteria and archaea: who they are, what they do, and how they do it
EGH Wagner, P Romby - Advances in genetics, 2015 - Elsevier
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …
Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica
The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …
Global transcriptional start site mapping using differential RNA sequencing reveals novel antisense RNAs in Escherichia coli
MK Thomason, T Bischler, SK Eisenbart… - Journal of …, 2015 - Am Soc Microbiol
While the model organism Escherichia coli has been the subject of intense study for
decades, the full complement of its RNAs is only now being examined. Here we describe a …
decades, the full complement of its RNAs is only now being examined. Here we describe a …
sRNA-mediated control of transcription termination in E. coli
N Sedlyarova, I Shamovsky, BK Bharati, V Epshtein… - Cell, 2016 - cell.com
Bacterial small RNAs (sRNAs) have been implicated in various aspects of post-
transcriptional gene regulation. Here, we demonstrate that sRNAs also act at the level of …
transcriptional gene regulation. Here, we demonstrate that sRNAs also act at the level of …
Pervasive transcription: illuminating the dark matter of bacterial transcriptomes
JT Wade, DC Grainger - Nature Reviews Microbiology, 2014 - nature.com
The conventional view of transcription posits that mRNAs are generated from the coding
DNA strand and are delineated by gene boundaries; however, recent reports have mapped …
DNA strand and are delineated by gene boundaries; however, recent reports have mapped …
Unprecedented high-resolution view of bacterial operon architecture revealed by RNA sequencing
T Conway, JP Creecy, SM Maddox, JE Grissom… - MBio, 2014 - Am Soc Microbiol
We analyzed the transcriptome of Escherichia coli K-12 by strand-specific RNA sequencing
at single-nucleotide resolution during steady-state (logarithmic-phase) growth and upon …
at single-nucleotide resolution during steady-state (logarithmic-phase) growth and upon …
RNA-binding proteins driving the regulatory activity of small non-coding RNAs in bacteria
Small non-coding RNAs (sRNAs) are critical post-transcriptional regulators of gene
expression. Distinct RNA-binding proteins (RBPs) influence the processing, stability and …
expression. Distinct RNA-binding proteins (RBPs) influence the processing, stability and …
m6A modification prevents formation of endogenous double-stranded RNAs and deleterious innate immune responses during hematopoietic development
Summary N 6-methyladenosine (m 6 A) is the most abundant RNA modification, but little is
known about its role in mammalian hematopoietic development. Here, we show that …
known about its role in mammalian hematopoietic development. Here, we show that …