Unnatural helical peptidic foldamers have attracted considerable attention owing to their
unique folding behaviours, diverse artificial protein binding mechanisms, and promising …

The extraordinary rate accelerations and control of reactivity exhibited by enzymes have
long inspired efforts to develop synthetic catalysts. Foldamers, which are oligomers with a …

The first general asymmetric synthesis of γ, γ‐disubstituted γ‐amino acids by copper‐
catalyzed ring opening of nonstrained lactones with amines is reported. This approach …

One of the most powerful strategies for the preparation of nanotubes is based on the
stacking of flat-shaped cyclic peptide components. This strategy allows precise control of the …

We report the first NMR and X‐ray diffraction (XRD) structures of an unusual 13/11‐helix
(alternating i, i+ 1 {NH− O= C} and i, i+ 3 {C= O− H− N} H‐bonds) formed by a heteromeric 1 …

Symmetrical oligourea foldamers were made from meso cyclohexane-1, 2-diamine and
desymmetrised by incorporating terminal functional groups (carbamates, ureas or thioureas) …

Antimicrobial peptides (AMPs) are expected to be good candidate molecules for novel
antimicrobial therapies. Most AMPs exert their antimicrobial activity through disruption of …

Poly-amido-saccharides (PAS) are carbohydrate-based, enantiopure synthetic polymers in
which sugar repeat units are joined by amide linkages. This unique and relatively rigid …

Abstract Oligoureas (up to n= 6) of meso cyclohexane‐1, 2‐diamine were synthesized by
chain extension with an enzymatically desymmetrized monomer 2. Despite being achiral …

Peptide-like foldamers controlled by normal amide backbone hydrogen bonding have been
extensively studied, and their folding patterns largely rely on configurational and …