Cancer neuroscience: State of the field, emerging directions

F Winkler, HS Venkatesh, M Amit, T Batchelor, IE Demir… - Cell, 2023 - cell.com
The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

The neuroscience of cancer

R Mancusi, M Monje - Nature, 2023 - nature.com
The nervous system regulates tissue stem and precursor populations throughout life.
Parallel to roles in development, the nervous system is emerging as a critical regulator of …

Neuron–oligodendroglial interactions in health and malignant disease

KR Taylor, M Monje - Nature Reviews Neuroscience, 2023 - nature.com
Experience sculpts brain structure and function. Activity-dependent modulation of the
myelinated infrastructure of the nervous system has emerged as a dimension of adaptive …

A prognostic neural epigenetic signature in high-grade glioma

R Drexler, R Khatri, T Sauvigny, M Mohme, CL Maire… - Nature Medicine, 2024 - nature.com
Neural–tumor interactions drive glioma growth as evidenced in preclinical models, but
clinical validation is limited. We present an epigenetically defined neural signature of …

[HTML][HTML] Cancer hallmarks intersect with neuroscience in the tumor microenvironment

D Hanahan, M Monje - Cancer cell, 2023 - cell.com
The mechanisms underlying the multistep process of tumorigenesis can be distilled into a
logical framework involving the acquisition of functional capabilities, the so-called hallmarks …

[HTML][HTML] Brain tumor networks in diffuse glioma

Y Yang, MC Schubert, T Kuner, W Wick, F Winkler… - …, 2022 - Elsevier
Diffuse gliomas are primary brain tumors associated with a poor prognosis. Cellular and
molecular mechanisms driving the invasive growth patterns and therapeutic resistance are …

Glioblastoma and brain connectivity: the need for a paradigm shift

A Salvalaggio, L Pini, A Bertoldo… - The Lancet Neurology, 2024 - thelancet.com
Despite substantial advances in cancer treatment, for patients with glioblastoma prognosis
remains bleak. The emerging field of cancer neuroscience reveals intricate functional …

Why do patients with cancer die?

A Boire, K Burke, TR Cox, T Guise… - Nature Reviews …, 2024 - nature.com
Cancer is a major cause of global mortality, both in affluent countries and increasingly in
developing nations. Many patients with cancer experience reduced life expectancy and …

Neuron–Glial Interactions in Health and Brain Cancer

Y Pan, M Monje - Advanced biology, 2022 - Wiley Online Library
Brain tumors are devastating diseases of the central nervous system. Brain tumor
pathogenesis depends on both tumor‐intrinsic oncogenic programs and extrinsic …

Leveraging next-generation materials for cancer neuroscience therapies in the central nervous system

JD Bernstock, BR Johnston, GK Friedman… - Nature Reviews …, 2024 - nature.com
Leveraging next-generation materials for cancer neuroscience therapies in the central nervous
system | Nature Reviews Materials Skip to main content Thank you for visiting nature.com. You …