GABA A receptors are the major inhibitory transmitter receptors in the brain. They are ligand-
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …

In this review we attempt to summarize experimental evidence on the existence of defined
native GABA A receptor subtypes and to produce a list of receptors that actually seem to …

This mini-review attempts to update experimental evidence on the existence of GABAA
receptor pharmacological subtypes and to produce a list of those native receptors that exist …

The cholinergic and glutamatergic neurotransmission systems are known to be severely
disrupted in Alzheimer's disease (AD). GABAergic neurotransmission, in contrast, is …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Publisher Summary This chapter describes the structure, pharmacology, and function of γ‐
aminobutyric acid type A (GABA A) receptor subtypes. GABA A receptors are the most …

The convulsant alkaloid bicuculline continues to be investigated more than 40 years after
the first publication of its action as an antagonist of receptors for the inhibitory …

GABAA receptor channels are ubiquitous in the mammalian central nervous system
mediating fast inhibitory neurotransmission by becoming permeant to chloride ions in …

There is a constant need for new therapies against multidrug resistant (MDR) cancer. An
attractive strategy is to develop chelators that display significant antitumor activity in …

The main inhibitory neurotransmitter system in the brain, the γ-aminobutyric acid (GABA)
system, is the target for many clinically used drugs to treat, for example, anxiety disorders …