Long-term outcomes in patients with chronic hepatitis C in the current era of direct-acting antiviral agents

L Wei, YH Huang - Expert review of anti-infective therapy, 2019 - Taylor & Francis
Introduction: Within the past decade, antiviral treatment for chronic hepatitis C virus (HCV)
infection has evolved from interferon (IFN)-based regimens to IFN-free oral direct-acting …

Effectiveness of direct‐acting agents for hepatitis C and liver stiffness changing after sustained virological response

FF Fernandes, J Piedade, L Guimaraes… - Journal of …, 2019 - Wiley Online Library
Abstract Background and Aim Few studies have evaluated sustained virological response
(SVR) rates by direct‐acting agents (DAAs) and liver stiffness measurement (LSM) changing …

Liver stiffness assessed by shear-wave elastography declines in parallel with immunoregulatory proteins in patients with chronic HCV infection during DAA therapy

G Peschel, J Grimm, C Buechler… - Clinical …, 2021 - content.iospress.com
BACKGROUND: A rapid decline of liver stiffness (LS) was detected by non-invasive
methods in patients with chronic hepatitis C (HCV) infection during treatment with direct …

Longitudinal assessment of the enhanced liver fibrosis score in the era of contemporary HIV and hepatitis C virus treatment

AR Gardner, Y Ma, P Bacchetti, JC Price… - The Journal of …, 2023 - academic.oup.com
Background The trajectory of liver fibrosis is not well understood in the contemporary era of
human immunodeficiency virus (HIV) and hepatitis C virus (HCV) therapy. Methods We …

Changes in liver stiffness and noninvasive fibrosis scores in Egyptian adolescents successfully treated with ledipasvir-sofosbuvir for chronic hepatitis C virus infection

DM Fahmy, M Shokeir, SM El Zeiny, MM Jonas… - The Journal of …, 2021 - Elsevier
Objective To assess changes in noninvasive liver fibrosis measurements after chronic
hepatitis C eradication by direct-acting antivirals in Egyptian adolescents. Study design Liver …

Improvement in liver stiffness in pediatric patients with hepatitis C virus after treatment with direct acting antivirals

EA Mogahed, H El-Karaksy, H Abdullatif… - The Journal of …, 2021 - Elsevier
Objectives To assess the degree of liver stiffness using transient elastography in Egyptian
children infected with hepatitis C virus (HCV) at baseline and 1 year after achievement of …

Early fibrosis regression by shear wave elastography after successful direct-acting anti-HCV therapy

MAS Kohla, AE Fayoumi, M Akl, M Abdelkareem… - Clinical and …, 2020 - Springer
Shear wave elastography (SWE) is a noninvasive ultrasound-based marker of hepatic
fibrosis not requiring a special device. Successful direct-acting anti-HCV therapy was …

[HTML][HTML] NS34A resistance-associated substitutions in chronic hepatitis C in Upper Egypt and regression of liver fibrosis after direct-acting antiviral therapy

NA Makhlouf, M Farouk, HM Nafeh, AFA Hasanain… - Egyptian Liver …, 2021 - Springer
Background Viral resistance-associated substitutions (RASs) can develop in the setting of
DAAs therapy (ie, emerging RASs). Long-term monitoring of fibrosis regression after …

[HTML][HTML] Effects of achieving sustained virologic response after direct-acting antiviral agents on long-term liver fibrosis in diabetics vs. in non-diabetic patients with …

MS Popescu, DM Firu, V Pădureanu, CM Mărginean… - Biomedicines, 2022 - mdpi.com
Because of the prevalence of HCV worldwide as well as its undiagnosed population due to
a lack of screening, HCV can be considered a modern pandemic disease. In 2016, the …

[HTML][HTML] Liver stiffness in chronic hepatitis C virus infection

RG Mihăilă - Romanian Journal of Internal Medicine, 2019 - sciendo.com
Introduction. The severity of liver fibrosis can be assessed noninvasively today by liver
stiffness measurements. Vibration-controlled transient elastography, shear wave …