Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis
in children have been reported worldwide, including 278 cases in the UK. Here we report an …

Nuclear DNA viruses simultaneously access cellular factors that aid their life cycle while
evading inhibitory factors by localizing to distinct nuclear sites. Adeno-associated viruses …

Nucleoside analogues acyclovir, valaciclovir, and famciclovir are the preferred drugs against
human Herpes Simplex Viruses (HSVs). However, the viruses rapidly develop resistance …

Adeno-associated virus type 2 (AAV2) is a small, non-pathogenic, helper virus-dependent
parvovirus with a single-stranded (ss) DNA genome of approximately 4.7 kb. AAV2 DNA …

Adeno-associated virus (AAV) is a small, non-pathogenic, helper virus-dependent
parvovirus with a single-stranded (ss) DNA genome of about 4.7 kb. AAV enters the cell after …

Adeno-associated Virus (AAV) depends on helper factors for productive replication. Upon
cell entry, it is thought to replicate its DNA through either the rolling circle or rolling hairpin …

Abstract The phosphoinositide 3-kinase (PI3K)/AKT pathway plays crucial roles in cell
viability and protein synthesis and is frequently co-opted by cytolytic viruses during their …

The two same-name members of the subfamily Alphaherpesvirinae, the human
herpesviruses Herpes simplex virus-1 (HSV-1) and Herpes simplex virus-2 (HSV-2), use …