Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

The widespread nature of several viruses is greatly credited to their rapidly altering RNA
genomes that enable the infection to persist despite challenges presented by host cells …

The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

GS-441524, an RNA‐dependent RNA polymerase (RdRp) inhibitor, is a 1′-CN-substituted
adenine C-nucleoside analog with broad-spectrum antiviral activity. However, the low oral …

The outbreak of coronavirus disease 2019 (COVID-19) has resulted in a global pandemic
due to the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has become a global health
crisis. Considering the recent food and drug administration (FDA) approval of remdesivir as …

There is a critical need for safe and effective drugs for COVID‐19. Only remdesivir has
received authorization for COVID‐19 and has been shown to improve outcomes but not …

Objectives We performed a systematic review and network meta-analysis of randomized
controlled trials (RCTs) to provide updated information regarding the clinical efficacy of …

Background and Purpose The SARS‐COV‐2 pandemic and the global spread of
coronavirus disease 2019 (COVID‐19) urgently call for efficient and safe antiviral treatment …

Abstract Emerging from Wuhan, China, SARS-CoV-2 is the new global threat that killed
millions of people, and many are still suffering. This pandemic has not only affected people …