Successful hematopoietic stem cell transplant requires the infusion of a sufficient number of
hematopoietic stem/progenitor cells (HSPCs) that are capable of homing to the bone marrow …

Hematopoietic progenitor cells can be mobilized from the bone marrow to the blood by a
wide variety of stimuli, including hematopoietic growth factors, chemotherapy, and …

Bone marrow (BM) transplantation still must overcome multiple difficulties and should benefit
from better understanding of stem-cell homing and mobilization. Here, we analyzed the …

Although the use of cytokine-mobilized peripheral blood stem cells has gained a significant
momentum in clinical transplantation, the mobilization schemes practiced are guided by a …

The findings that many primitive human hematopoietic cells give rise to daughter cells that
adopt different cell fates and/or show different proliferation kinetics suggest that …

HEMATOPOIESIS IS A complex process in which pluripo-tent stem cells proliferate and
differentiate to generate the full complement of mature blood cells. More than 30 …

The bone marrow microenvironment is a complex three dimensional structure where
hematopoietic stem cells proliferate, mature, migrate into the sinusoidal space, and enter the …

The mechanisms that regulate hematopoietic progenitor cell (HPC) mobilization from the
bone marrow to blood have not yet been defined. HPC mobilization by granulocyte colony …

Splenic marginal zone lymphoma (SMZL) is a specific low-grade small B-cell lymphoma that
is incorporated in the World Health Organization classification. Characteristic features are …

During ontogenesis and the entire adult life hematopoietic stem and progenitor cells have
the capability to migrate. In comparison to the process of peripheral leukocyte migration in …