The healing of diabetic foot ulcers (DFUs) is a major challenge for clinical treatment because
of the hyperglycemic and acidic microenvironment in the wound area. In this study, a self …

Regeneration is an elegant and complex process informed by both local and long-range
signals. Many current studies on regeneration are largely limited to investigations of local …

Diabetic foot ulcer (DFU) is one of the most serious complication of diabetes mellitus with the
characteristic of long-term non-healing wound, which often leads to amputation and …

Objective The quality of life of diabetic patients is seriously affected by wound healing
difficulty, which can lead to increased infection, skin deep tissue injury and continuous pain …

Introduction In recent years, insulin eye drops have attracted increasing attention from
researchers and ophthalmologists. The aim of this study was to investigate the efficacy and …

Autophagy plays a vital role in cell homeostasis by eliminating nonfunctional components
and promoting cell survival. Here, we examined the levels of autophagy signaling proteins …

Background: Insulin and insulin-like growth factor (IGF)-1 receptors are present in ocular
tissues such as corneal epithelium, keratocytes, and conjunctival cells. Insulin plays a …

This is the first study to evaluate the topical application of Lobelia alsinoides Lam (LT)
ethanolic extract on burns in rats. A deep third‐degree burn wound was inflicted in adult …

Ceramides are structural components of the stratum corneum that regulate cell proliferation
and differentiation. The study of the effect of the cream containing dexpanthenol and …

THERAPEUTIC CHALLENGE Pemphigus vulgaris (PV) is characterized by cutaneous
flaccid blisters, erosions, and crusts and mucosal erosions. 1 In severe PV, erosions may …