Aqueous solubility is essential for drug candidates. Poor aqueous solubility is likely to result
in poor absorption, even if the permeation rate is high, since the flux of a drug across the …

Synthetic chemists are constantly challenged to consider more environmentally benign
methods for generation of the desired target molecules. 1 Recently, there has been an …

Organic light emitters based on multiresonance-induced thermally activated delayed
fluorescent materials have great potential for realizing efficient, narrowband organic light …

Solubility plays a critical role in many aspects of research (drugs to materials). Solubility
parameters are very useful for selecting appropriate solvents/non-solvents for various …

Alzheimer's disease is a major public brain condition that has resulted in many deaths, as
revealed by the World Health Organization (WHO). Conventional Alzheimer's treatments …

A series of pyrenes sandwiched by axially chiral 1, 1′-binaphthyls were synthesized.
Among them,(R, R)-3 possessing 2-hydroxy-3, 3′-dimethylbinaphthyls exhibited solvent …

Herein, we describe a practical protocol for the removal of alcohol functional groups through
reductive cleavage of their benzoate ester analogs. This transformation requires a strong …

We have recently reported on several Fe catalysts for N2-to-NH3 conversion that operate at
low temperature (− 78° C) and atmospheric pressure while relying on a very strong …

A porphyrin/rhenium complex dyad, ZnP-phen= Re, in which the 2-position of the 1, 10-
phenanthroline (phen) of fac-Re (phen)(CO) 3Br is directly connected with the meso-position …

The late-stage functionalization (LSF) of pharmaceutical and agrochemical compounds by
the site-selective activation of C–H bonds provides access to diverse structural analogs and …