Thiazole ring—A biologically active scaffold

A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

An overview of the synthesis and antimicrobial, antiprotozoal, and antitumor activity of thiazole and bisthiazole derivatives

AM Borcea, I Ionuț, O Crișan, O Oniga - Molecules, 2021 - mdpi.com
Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …

Recent applications of 1, 3-thiazole core structure in the identification of new lead compounds and drug discovery

A Ayati, S Emami, A Asadipour, A Shafiee… - European Journal of …, 2015 - Elsevier
Thiazole is one of the most important scaffolds in heterocyclic chemistry and drug design
and discovery. It is widely found in diverse pharmacologically active substances and in …

Heterogeneous graphitic carbon nitrides in visible-light-initiated organic transformations

SK Verma, R Verma, YR Girish, F Xue, L Yan… - Green …, 2022 - pubs.rsc.org
In recent years, g-C3N4 photocatalyst-mediated organic reactions have represented an
important mode of chemical transformations and are expected to become a crucial field at …

A key review on oxadiazole analogs as potential methicillin-resistant Staphylococcus aureus (MRSA) activity: Structure-activity relationship studies

SK Verma, R Verma, KSS Kumar, L Banjare… - European journal of …, 2021 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming dangerous to human
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …

Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies

GF Zha, HD Preetham, S Rangappa, KSS Kumar… - Bioorganic …, 2021 - Elsevier
Small molecule based inhibitors development is a growing field in medicinal chemistry. In
recent years, different heterocyclic derivatives have been designed to counter the infections …

Structure-activity relationship studies of thiazole agents with potential anti methicillin-resistance Staphylococcus aureus (MRSA) activity

J Wang, S Long, Z Liu, KP Rakesh, R Verma… - Process …, 2023 - Elsevier
Due to the increasing resistance of methicillin-resistant Staphylococcus aureus (MRSA) to
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …

Programmed synthesis of arylthiazoles through sequential C–H couplings

S Tani, TN Uehara, J Yamaguchi, K Itami - Chemical Science, 2014 - pubs.rsc.org
A programmed synthesis of privileged arylthiazoles via sequential C–H couplings catalyzed
by palladium or nickel catalysts has been accomplished. This versatile protocol can supply …

Regioselective synthesis of 2, 5-disubstituted-1, 3, 4-thiadiazoles and 1, 3, 4-oxadiazoles via alkyl 2-(methylthio)-2-thioxoacetates and alkyl 2-amino-2-thioxoacetates

C Santhosh, KR Singh, K Sheela… - The Journal of …, 2023 - ACS Publications
An acid-catalyzed regioselective cyclization reaction of 2, 5-disubstituted-1, 3, 4-thiadiazoles
and 1, 3, 4-oxadiazoles has been developed. The synthetic precursors alkyl 2-(methylthio)-2 …

The regioselective synthesis of 2, 5-and 4, 5-disubstituted thiazoles via the cyclization of 2-oxo-2-(amino) ethanedithioates with isocyanides

KR Singh, C Santhosh, TR Swaroop… - Organic & Biomolecular …, 2022 - pubs.rsc.org
The regioselective synthesis of 2-(methylthio)-N-aryl/alkylthiazole-5-carboxamides and ethyl-
5-(aryl/alkyl carbamoyl) thiazole-4-carboxylates was carried out via the base-induced …