Thiazole ring—A biologically active scaffold
A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …
applications. Its derivatives have a wide range of biological activities such as antioxidant …
An overview of the synthesis and antimicrobial, antiprotozoal, and antitumor activity of thiazole and bisthiazole derivatives
Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …
Recent applications of 1, 3-thiazole core structure in the identification of new lead compounds and drug discovery
Thiazole is one of the most important scaffolds in heterocyclic chemistry and drug design
and discovery. It is widely found in diverse pharmacologically active substances and in …
and discovery. It is widely found in diverse pharmacologically active substances and in …
Heterogeneous graphitic carbon nitrides in visible-light-initiated organic transformations
In recent years, g-C3N4 photocatalyst-mediated organic reactions have represented an
important mode of chemical transformations and are expected to become a crucial field at …
important mode of chemical transformations and are expected to become a crucial field at …
A key review on oxadiazole analogs as potential methicillin-resistant Staphylococcus aureus (MRSA) activity: Structure-activity relationship studies
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming dangerous to human
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …
Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies
Small molecule based inhibitors development is a growing field in medicinal chemistry. In
recent years, different heterocyclic derivatives have been designed to counter the infections …
recent years, different heterocyclic derivatives have been designed to counter the infections …
Structure-activity relationship studies of thiazole agents with potential anti methicillin-resistance Staphylococcus aureus (MRSA) activity
Due to the increasing resistance of methicillin-resistant Staphylococcus aureus (MRSA) to
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …
Programmed synthesis of arylthiazoles through sequential C–H couplings
S Tani, TN Uehara, J Yamaguchi, K Itami - Chemical Science, 2014 - pubs.rsc.org
A programmed synthesis of privileged arylthiazoles via sequential C–H couplings catalyzed
by palladium or nickel catalysts has been accomplished. This versatile protocol can supply …
by palladium or nickel catalysts has been accomplished. This versatile protocol can supply …
Regioselective synthesis of 2, 5-disubstituted-1, 3, 4-thiadiazoles and 1, 3, 4-oxadiazoles via alkyl 2-(methylthio)-2-thioxoacetates and alkyl 2-amino-2-thioxoacetates
C Santhosh, KR Singh, K Sheela… - The Journal of …, 2023 - ACS Publications
An acid-catalyzed regioselective cyclization reaction of 2, 5-disubstituted-1, 3, 4-thiadiazoles
and 1, 3, 4-oxadiazoles has been developed. The synthetic precursors alkyl 2-(methylthio)-2 …
and 1, 3, 4-oxadiazoles has been developed. The synthetic precursors alkyl 2-(methylthio)-2 …
The regioselective synthesis of 2, 5-and 4, 5-disubstituted thiazoles via the cyclization of 2-oxo-2-(amino) ethanedithioates with isocyanides
KR Singh, C Santhosh, TR Swaroop… - Organic & Biomolecular …, 2022 - pubs.rsc.org
The regioselective synthesis of 2-(methylthio)-N-aryl/alkylthiazole-5-carboxamides and ethyl-
5-(aryl/alkyl carbamoyl) thiazole-4-carboxylates was carried out via the base-induced …
5-(aryl/alkyl carbamoyl) thiazole-4-carboxylates was carried out via the base-induced …